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| Application value of ultrasonography in the diagnosis of liver fibrosis in patients with viral hepatitis |
| XIE Xiao-qin |
| Department of Ultrasound, Pingxiang No.2 People′s Hospital, Jiangxi Province, Pingxiang 337000, China |
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Abstract Objective To explore the application value of ultrasonography in the diagnosis of liver fibrosis in patients with viral hepatitis.Methods A total of 50 patients with viral hepatitis admitted to our hospital from January 2018 to January 2019 were selected as the research objects, and were divided into 5 stages according to the results of puncture biopsies：no liver fibrosis to liver cirrhosis (S0-S4).The biopsies were divided into 4 grades (G1-G4) according to inflammation.The differences in the ultrasound indicators (maximum velocity of portal vein, thickness of gallbladder wall,long diameter of spleen and inner diameter of portal vein trunk) were compared.Results In the whole ultrasonic qualitative index structure, the distribution and morphology of light spots in liver parenchyma were abnormal, and the echo of liver surface was related to the grade of inflammation.However, in view of these qualitative indexes, there was a great variation in the diagnosis and judgment of specific patients.Among the degree of liver fibrosis, there were differences in the diameter of spleen portal vein and the length of spleen (P＜0.05).The limit value of the spleen′s long diameter was 12.1 cm, and the specificity and sensitivity for the diagnosis of early cirrhosis were 75.2% and 60.0%, respectively.Taking the splenic vein inner diameter of 8 mm as the limit value, the specificity and sensitivity for the diagnosis of early cirrhosis were 78.0% and 60.0% respectively.When the limit value of inner diameter of portal vein trunk was 12 mm, the specificity and sensitivity in the diagnosis of early liver cirrhosis were 44.5% and 76.6%.If the limit value of maximum velocity of portal vein was 30.5 cm/s, the specificity and sensitivity for the diagnosis of early liver cirrhosis were 66.8% and 78.5%, respectively.Conclusion Ultrasonography is practical and efficient in the diagnosis of liver fibrosis in viral hepatitis, with outstanding clinical application value.
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