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| Effect of selective cervical cerclage combined with Phloroglucinol on pregnancy outcome and newborn of pregnant women with cervical insufficiency |
| WU Guo-ying LU Shun-qiong WANG Bin |
| Department of Obstetrics and Gynecology, Zhaoqing First People′s Hospital in Guangdong Province, Zhaoqing 526000,China |
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Abstract Objective To investigate the effect of selective cervical cerclage combined with Phloroglucinol on pregnancy outcome and neonatal outcome of pregnant women with cervical insufficiency (CIC).Methods A total of 45 pregnant women with CIC admitted to our department from January 2015 to June 2018 were selected as the subjects, and divided into control group (n=22) and observation group (n=23) by random number table method.The control group used expectant therapy, and the observation group were given selective cervical cerclage combined with Phloroglucinol, the two groups were all followed up until the end of pregnancy.The neonatal prognosis and pregnancy outcomes were compared between the two groups.According to the period of operation, the pregnant women of observation group were divided into group A (12-16 weeks of gestation, 13 cases) and group B (more than 16 to 24 weeks of gestation, 10 cases).The neonatal prognosis and pregnancy outcomes were compared between the two groups.Results The neonatal survival rate,birth weight and 5 min Apgar score in the observation group were higher than those in the control group, and the asphyxia rate was lower than that in the control group, the differences were statistically significant (P<0.05).The gestational week and full-term rate of delivery in the observation group were higher than those in the control group, and the abortion rate and premature delivery rate were lower than those in the control group, the differences were statistically significant (P<0.05).The full-term rate of group A was higher than that of group B, while the premature rate was lower than that of group B, the differences were statistically significant (P<0.05).Conclusion Selective cervical cerclage combined with Phloroglucinol can prolong the gestational age of CIC patients, effectively improve the prognosis and pregnancy outcomes of neonates, and the effect of early pregnancy surgery is better.
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