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| Clinical effect of Pediatric Compound Amino Acid Injection combined with Racecadotril Granules on children with rotavirus enteritis |
| WU Yuan-fang HUANG Hui-yi YU Shu-juan |
| Department of Pediatrics,Kaiping Central Hospital,Guangdong Province,Kaiping 529300,China |
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Abstract Objective To study the clinical effect of Pediatric Compound Amino Acid Injection(18AA-Ⅱ)combined with Racecadotril Granules on children with rotavirus enteritis.Methods A total of 150 children with rotavirus enteritis treated in our hospital from March 2017 to January 2018 were selected as study subjects.They were divided into test group(n=75)and control group(n=75)by random number table method.The children in the control group were treated with conventional anti-inflammatory and antiviral and fluid replacement.The test group was treated with 18AA-Ⅱwith Racecadotril Granules on the basis of conventional treatment.The clinical effect,clinical symptom improvement time and serum C-reactive protein(CRP)levels at different periods of the two groups were compared.Results After treatment,the total clinical effective rate of patients in the test group was 90.67%,higher than that of the control group accounting for 76.00%,the difference was statistically significant(P＜0.05).The corrected dehydration time,antidiarrheal time,antipyretic time and vomiting stopping time in the test group were shorter than those in the control group,the differences were statistically significant(P＜0.05).CRP levels of the children in the test group at 24,48,and 72 h after treatments were lower than those in the control group,the difference was statistically significant(P＜0.05).Conclusion The 18AA-Ⅱcombined with Racecadotril Granules in children with rotavirus enteritis has a good clinical effect,which can effectively shorten the symptom relief time and enhance the anti-inflammatory effect.
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