静脉输注右美托咪定在小儿全凭静脉麻醉术后躁动的应用效果

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Abstract Objective To observe the effect of Dexmedetomidine on postoperative emergence agitation in the children undergoing tonsillectomy and adenoidectomy with total intravenous anesthesia.Methods Sixty children with total intravenous anesthesia who underwent tonsillectomy and adenoidectomy in Mentougou District Hospital from February 2014 to February 2016 were selected as the research objects.They were divided into Dexmedetomidine group(n=30)and control group(n=30)according to the random number table method.Patients in the Dexmedetomidine group received intravenous Dexmedetomidine 0.5μg/(kg·h),and patients in the control group received saline.The anesthesia time and recovery time of the two groups were recorded.The scores of children′s and infants′postoperative pain scale(CHIPPS)and pediatric anesthesia emergence delirium scale(PAED)were compared between the two groups at the time of recovery and 15,30min after recovery.At the same time,the incidence of nausea and vomiting was observed and compared between the two groups.The incidence rates of CHIPPS score＞3 points and PAED score＞12 points were recorded between the two groups.Results The CHIPPS scores of children in Dexmedetomidine group at the time of recovery and 15,30 min after recovery were lower than those in the control group,and the differences were statistically significant(P＜0.05).The PEAD scores of children in Dexmedetomidine group at the time of recovery and 15,30min after recovery were lower than those of the control group,and the differences were statistically significant(P＜0.05).There were no statistically significant differences between the two groups in the time of anesthesia,the incidence of nausea and vomiting during awaking,the incidence of CHIPPS score＞3 points and the incidence of PAED score＞12 points(P＞0.05).The recovery time of Dexmedetomidine group was longer than that of the control group,and the difference was statistically significant(P＜0.05).Conclusion Dexmedetomidine can decrease the postoperative emergence agitation in the children undergoing tonsillectomy and adenoidectomy with total intravenous anesthesia.

Key words： Children Dexmedetomidine Total intravenous anesthesia Adenotonsillectomy Postoperative emergence agitation

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	CAO Li-qun
	WANG Jin-fei
	DU Hua-juan
	GONG Li-na

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CAO Li-qun,WANG Jin-fei,DU Hua-juan, et al. Application effect of intravenous Dexmedetom idine on postoperative emergence agitation in the children with total intravenous anesthesia[J]. 中国当代医药, 2020, 27(9): 107-110.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2020/V27/I9/107

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