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| Effect of blood glucose on first implantation pacing parameters of patients undergoing permanent pacemaker implantation |
| MO Hai-liang WU Zi-jun HUANG Rui-na CHEN Lu-jun SUN Qi-fan WU Keng▲ |
| The First Department of Cardiology,the Affiliated Hospital of Guangdong Medical University,Zhanjiang 525000,China |
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Abstract Objective To investigate the effect of blood glucose on first implantation pacing parameters of patients undergoing permanent pacemaker implantation.Methods A total of 231 patients undergoing permanent pacemaker implantation treated in the hospital from March 2014 to March 2019 were selected as the subjects,and retrospective analysis was conducted.According to the blood glucose,they were divided into group A(patients with diabetes,42 cases),group B(patients with impaired glucose tolerance,118 cases)and group C(patients with normal blood glucose,71 cases).The pacing threshold,perception,impedance,program-controlled test time of pacemaker parameters were compared among the three groups.The correlation between blood glucose and pacing parameterswas analyzed.Results The ventricular pacing threshold,perception,impedance in group A and group B were higher than those in group C,and the program-controlled test time of parameters was longer than that in group C,and the differences were statistically significant(P＜0.05).There was no statistically significant difference in ventricular pacing threshold,perception or impedance between the group A and group B(P＞0.05).The ventricular parameter programmable test time in group A was longer than that of group B,the difference was statistically significant(P＜0.05).The levels of fasting blood glucose(FBG)and blood glucose 2 hours aftermeal(2 h BG)in group A and group B were higher than those in group C,and the FBG and 2 h BG levels of group A were higher than those of group B,the differences were statistically significant(P＜0.05).Spearman correlation analysis showed that FBG was positively correlated with pacing threshold,perception,impedance and program-controlled test time of parameters(r=0.410,0.352,0.332,0.318;P＜0.05).And 2 h BG was positively correlated with the pacing threshold,perception,impedance and program-controlled test time of parameters(r=0.425,0.367,0.346,0.327;P＜0.05).Conclusion Blood glucose has influence on the pacing threshold,impedance and perception of patients undergoing pacemaker implantation.High blood glucose will lead to elevated pacing threshold and impedance,decreased sensitivity and prolongation of program-controlled test time of parameters.
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