生血宝合剂联合补铁剂在单侧或双侧人工全髋关节置换术后贫血患者中的应用效果

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Abstract Objective To investigate the application effect of Shengxuebao Mixture combined with iron supplement in patients with anemia after unilateral or bilateral total hip arthroplasty. Methods A total of 124 patients who underwent unilateral or bilateral total hip arthroplasty and had anemia after surgery in our hospital from January 2018 to May 2019 were selected as the research objects, they were randomly divided into the control group and observation group,62 cases in each group. The control group received an intravenous infusion of Iron Sucrose Solution, the observation group received a combination of Iron Sucrose Solution and Shengxuebao Mixture. The blood index before and after operation, treatment effect, traditional Chinese medicine symptom score treatment effect, hip joint function (Harris) score,and adverse drug reactions were compared between the two groups. Results The RBC of the two groups at 1,7,14 days after operation were lower than those before operation, the differences were statistically significant (P ＜0.05). The hemoglobin (HB) level of the observation group at 1, 7 days after operation were lower than those of before operation,The Hb level of the control group at 1,7,14 days after operation were lower than those of before operation, the differences were statistically significant (P＜0.05). The hematocrit (HCT) of the observation group at 1 day after operation was lower than that of before operation, the HCT of the control group at 1, 7 days after operation were lower than those of before operation, the differences were statistically significant (P＜0.05). The RBC, Hb and HCT of the observation group were higher than those of the control group at 7, 14 days after operation, the differences were statistically significant(P＜0.05). The total effective rate of the observation group was higher than that of the control group, the difference was statistically significant (P＜0.05). The total effective rate of traditional chinese medicine symptom score in the observation group was higher than that in the control group, the difference was statistically significant (P＜0.05). The Har-ris score of the observation group at 7 and 14 days after operation were higher than those of the control group, the differences were statistically significant (P＜0.05). There was no significant difference of the incidence of adverse reactions between the two groups (P＞0.05). Conclusion The combination of Shengxuebao Mixture and iron supplement for anemia after total hip arthroplasty can improve patients′ hematological indexes, traditional chinese medicine symptoms, and hip function, improve the treatment effect of patients, and do not increase the incidence of adverse reactions. It is worthy of clinical application.

Key words： Total hip arthroplasty Anemia Shengxuebao Mixture Iron supplement Effect observation

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