七氟醚吸入麻醉与丙泊酚静脉麻醉对老年腹腔镜胆囊切除患者的麻醉效果比较

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Abstract Objective To compare the anesthetic effect of Sevoflurane inhalation anesthesia and Propofol intravenous anesthesia in elderly patients with laparoscopic cholecystectomy. Methods A total of 100 elderly patients undergoing laparoscopic cholecystectomy in our hospital from February 2018 to February 2019 were selected as the research subjects, and they were divided into control group (n=50) and research group (n=50) by random number table method. Patients in the control group were provided with Propofol anesthesia, and patients in the research group were anesthetized with inhalation of Sevoflurane. The anesthetic effect of the two groups were compared. The postoperative anaesthesia recovery, extubation and recovery time of the two groups were compared. The mini-mental state examination scale(MMSE) scores of the two groups were compared at different time points after operation. Visual analogue scale (VAS)scores were compared between the two groups at different time points after surgery. Results The excellent anesthesia rate of patients in the research group was 98.00%, which was higher than that in the control group (76.00%), the difference was statistically significant (P＜0.05). The postoperative anesthesia recovery time of patients in the research group was (16.85±3.05) min, the post-extubation time was (23.50±3.80) min, and the post-operative recovery time was(23.65±4.70) min, which were shorter than those of the control group ([20.65±3.55], [27.85±4.65], [27.95±4.80] min),the differences were statistically significant (P＜0.05). The MMSE score at 1 h postoperatively of the patients in the research group was (28.35±0.35) points, the MMSE score at 4 h postoperatively was (27.45±1.25) points, and the MMSE score at 12 h postoperatively was (27.85±1.15) points, which were higher than those in the control group ([22.95±2.50],[23.85±1.40], [25.95±1.20] points), the differences were statistically significant (P＜0.05). There was no significant difference in MMSE scores between the research group and the control group at 24 and 48 h postoperatively (P＞0.05). In the research group, the VAS score score at 1 h postoperatively was (1.25±0.40) points, the VAS score score at 4 h postoperatively was (2.15±0.55) points, the VAS score score at 12 h postoperatively was (2.15±0.45) points, the VAS score score at 24 h postoperatively was (1.88±0.60) points, and the VAS score score at 48 h postoperatively was (1.45±0.55) points, which were not displayed statistical significance compared with the control group ([1.23±0.45], [2.09±0.60], [2.19±0.40], [1.93±0.55], [1.48±0.50] points), respectively (P＞0.05). Conclusion Compared with Propofol intravenous anesthesia, the effect of Sevoflurane inhalation anesthesia in elderly patients undergoing laparoscopic cholecystectomy is remarkable.

Key words： Sevoflurane inhalation anesthesia Propofol intravenous anesthesia Elderly patients Laparoscopic cholecystectomy Anesthetic effect

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LI Jun-shi. Anesthetic effect comparison of Sevoflurane inhalation anesthesia with Propofol intravenous anesthesia in elderly patients undergoing laparoscopic cholecystectomy[J]. 中国当代医药, 2020, 27(7): 154-157.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2020/V27/I7/154

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