早期护理在子痫期间伴血栓形成倾向孕妇中的应用效果

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Abstract Objective To explore the application effect of early nursing on pregnant women with eclampsia and thrombosis tendency.Methods A total of 68 pregnant women with thrombophilia who admitted to our hospital from January 2015 to December 2017 were enrolled in this study.The patients were divided into two groups,34 patients each group.In control group,routine nursing was used,while in observation group,early nursing intervention was adopted.The coagulation index,thrombus marker,platelet activation index and complication rate of the two groups were compared and analyzed.Results Participants were all delivered successfully without maternal and child death.After nursing,the prothrombin time(PT)and activated partial thromboplastin time(APTT)of the observation group were significantly longer compared with those in the control group.The fibrinogen (FBG)level of the observation group was significantly lower than that of the control group with statistical significance(P＜0.05).There was no significant difference in thrombin time(TT)between the two groups(P＞0.05).After nursing,the plasminogen activity(PLG)and antithrombin activity(AT)of the observation group were both significantly higher than those of the control group with significant differences (P＜0.05).The D-dimer(D-D)level of the observation group was much lower than that of the control group,with significant difference(P＜0.05).After nursing,lysosomal membrane glycoprotein(CD63)and platelet alpha granule membrane glycoprotein (CD62p)were significantly lower in the observation group than that in the control group (P＜0.05).The total incidence of postpartum complications in the observation group was significantly lower than that in the control group(P＜0.05).Conclusion Early care for pregnant women with eclampsia and thrombosis tendency can optimize the patient′s coagulation indexes,thrombus markers and platelet activation indexes in a low incidence of postpartum complications,which is worthy of further clinical application.

Key words： Early nursing Eclampsia Thrombosis Pregnant women

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	XU Hui-zhen
	HUANG Yong
	LIN Hui-mei

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XU Hui-zhen,HUANG Yong,LIN Hui-mei. Application effect of early nursing on pregnant women with eclampsia and thrombosis tendency[J]. 中国当代医药, 2019, 26(8): 241-243.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2019/V26/I8/241

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