不同出生体重新生儿第1天血小板及凝血功能的分析

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Abstract Objective To study the clinical significance of the platelet(PLT)and blood coagulation function on the first day of birth in neonates with different birth weight.Methods A total of 200 newborns born in our hospital from January to October in 2017 were selected as study object,then they were divided into the very low birth weight infant group(32 infants),the low birth weight group(58 infants),the normal birth weight infant group(69 infants),and the macrosomia infant group (41 infants).Altogether 50 full-term neonates during the same period were selected as the control group.The platelet and blood coagulation function were examined in each group within the first day after birth,and the PLT and blood coagulation function of the newborns in each group were compared.Results There was statistically significant difference in the level of PLT,prothrombin time(PT),prothrombin time activity(PTA),international normalized ratio(INR)and activated partial thromboplastin time(APTT)among each groups(P＜0.05).There was no significant difference in thrombin time (TT)and fibrinogen (FIB)levels among groups (P＞0.05).The PLT level of the very low birth weight infant group was lower than that of the low birth weight infant group,the normal birth weight infant group,the macrosomia infant group and the control group,the difference was statistically significant(P＜0.05).The levels of PT,INR and APTT in the very low birth weight infant group were higher than those in the low birth weight infant group,the normal birth weight infant group,the macrosomia infant group and the control group,the difference was statistically significant(P＜0.05).Conclusion Abnormal in PLT and coagulation function on the first day of birth may be one of the indicators of increased risk of intraventricular hemorrhage in very low birth weight infants.

Key words： Platelet Blood coagulation function Very low birth weight infants

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	YANG Shi-mei
	WEI Chun-hui
	ZHANG Yan-shun

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YANG Shi-mei,WEI Chun-hui,ZHANG Yan-shun. Analysis of platelet and blood coagulation function on the first day of birth in neonates with different birth weight[J]. 中国当代医药, 2019, 26(8): 109-111.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2019/V26/I8/109

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