内脂素水平与多囊卵巢综合征的相关性研究

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Abstract Objective To investigate the correlation between visfatin level and polycystic ovary syndrome(PCOS).Methods A total of 30 patients with PCOS from February 2016 to June 2018 in the Gynecological Clinic of People′s Hospital of Luohu District in Shenzhen City were selected as the experimental group,they were divided into the PCOS obesity group(10 cases)and the PCOS non-obesity group(20 cases).Meanwhile,30 normal women in the physical examination center were selected as the control group.The control group was divided into the control obesity group(10 cases)and the control non-obesity group(20 cases).The general data,plasma visfatin concentration,insulin concentration,blood glucose concentration and testosterone content of each group were compared,and the relationship between each factor and visfatin was further analyzed.Results There was no significant difference in age and height between all groups(P＞0.05).The levels of testosterone,insulin and visfatin in the PCOS obesity group and the PCOS non-obesity group were significantly higher than those in the control obesity group and the control non-obesity group,with significant difference (P＜0.05).Pearson correlation analysis showed that serum visfatin content was positively correlated with BMI,WHR,testosterone concentration and insulin content(r=0.308,0.179,0.359,0.352,P＜0.05).Conclusion As a kind of adipose cytokine,visfatin plays an important role in the pathogenesis of PCOS.It is not only one of the clinicopathological characteristics of PCOS,but also closely related to obesity,insulin resistance and hyperandrogenism.Meanwhile,visfatin can affect the occurrence and development of many metabolic diseases,such as PCOS.

Key words： Visfatin Polycystic ovary syndrome Insulin resistance Obesity

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	ZHANG Wen-bo
	LI Bao-yan

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ZHANG Wen-bo,LI Bao-yan. Study on correlation between visfatin level and polycystic ovary syndrome[J]. 中国当代医药, 2019, 26(8): 87-89.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2019/V26/I8/87

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