Objective To summarize and analyze the clinical features of bacterial liver abscess and provide evidence for rational diagnosis and treatment.Methods The clinical data of 69 cases patients with bacterial liver abscess treated in our hospital from January 2015 to December 2017 were retrospectively analyzed and descriptively studied.Results The average age of patients was(56.53±12.88)years old.The highest peak age of bacterial liver abscess onset was 50-69 years old(59.42%).There were 58 patients with one or more underlying diseases and mostly complicated with diabetes mellitus(n=32,46.38%).The main clinical manifestations of patients with liver abscess were fever(n=62,89.86%),followed by fear of cold and chills(n=42,60.87%)and right upper quadrant pain(n=29,40.03%).Among the patients,single-lumen right lobe abscess was common(n=52,75.36%).The percentages of neutrophils increase and albumin reduction were the most remarkable in laboratory abnormalities,92.75%(64/69)and 78.26%(54/69),respectively.Twenty-four patients underwent blood culture and 15 were positive (62.50%).Thirty-six patients underwent bacteriological culture from pus puncturing and 29 were positive(80.56%).The blood culture and pus culture results were Klebsiella pneumonia in 5 patients.The treatment method is mainly based on antibacterial drugs combined with percutaneous puncture drainage.Forty patients were cured and 26 ones were improved,with a total effectiveness rate of 95.65%.Conclusion Bacterial liver abscess occurs in middle-aged and elderly people.The main clinical manifestations are high fever,fear of cold and chills,right upper quadrant pain.The main pathogen is Klebsiella pneumoniae.Perfect abdominal color Doppler ultrasound and upper abdominal CT can assist in the early diagnosis of bacterial liver abscess.