磁共振扩散加权成像联合磁共振波谱分析检查对前列腺病变性质的诊断价值

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Abstract Objective To explore the diagnostic value of diffusion weighted magnetic resonance imaging （DWI）combined with magnetic resonance spectroscopy （MRS）in the nature and type of prostatic lesions.Methods Thirty-eight patients diagnosed as prostate cancer（PCa）in chaonan Minsheng hospital pf shantou from January 2016 to September 2018 were selected as observation group and 38 patients diagnosed as BPH as control group.DWI，MRS and DWI combined with MRS were performed in both groups.The difference of ADC value and （Cho+cre）/Cit value between the two groups was observed.The diagnostic results of DWI，MRS and DWI combined with MRS and the diagnostic coincidence rate were compared between the two groups.Results The ADC value of the observation group at 400 s/mm2was（0.86±0.28），significantly lower than that of the control group，the 800 s/mm2was（0.74±0.39），significantly lower than that of the control group，the differences were statistically significant（P＜0.001）.The Cho+cre/Cit value in the observation group was significantly higher than that in the control group，the difference was statistically significant（P＜0.001）.Pathological results of 76 patients：45 cases of prostate cancer and 31 cases of benign prostatic hyperplasia.Compared with pathological results，36 cases were diagnosed positive by DWI and 40 cases were negative，38 cases were diagnosed positive by MRS and 38 cases were negative，36 cases were diagnosed positive by DWI combined with MRS，and 30 cases were negative.The sensitivity，specificity and accuracy of combined DWI and MRS in the diagnosis of prostate cancer were 94.74%，92.11%and 92.11%，respectively，the sensitivity，specificity and accuracy of combined examination were significantly higher than those of DWI and MRS alone，the differences were statistically significant（P＜0.05）.Conclusion Both DWI and MRS can effectively diagnose PCa and BPH，can accurately distinguish between PCa and BPH patients，but MRS combined with DWI has higher diagnostic accuracy for prostate cancer，it can clearly show the relationship between the microstructure and metabolic level of prostate tissue.It is superior to DWI and MRS alone.It has important significance in clinical diagnosis and can provide important basis for early diagnosis.

Key words： Diffusion-weighted magnetic resonance imaging （DWI） Magnetic resonance spectroscopy analysis of（MRS） Prostate cancer Prostatic hyperplasia Diagnostic accordance rate

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	Articles by authors
	GUO Zuo-liang
	MA Xing-can
	CHEN Ning
	MA Shu-hua

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GUO Zuo-liang,MA Xing-can,CHEN Ning, et al. Diagnostic value of diffusion-weighted magnetic resonance imaging combined with magnetic resonance spectroscopy in the nature of prostatic lesions[J]. 中国当代医药, 2019, 26(6): 92-95.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2019/V26/I6/92

［1］	张雪红，张期莲，符惠宏，等.MR弥散加权成像表观弥散系数在前列腺病变诊断中的临床价值［J］.医学影像学杂志，2017，27（5）：972-974.
［2］	Tommaso C，Ivan RG，Giulio R，et al.Metabolic syndrome and prostatic disease：potentially role of polyphenols in preventive strategies.A review［J］.Int Braz J Urol，2016，42（3）：422-430.
［3］	李慧燕，郑泽宇，许乙凯.前列腺疾病的多参数磁共振成像［J］.实用医学杂志，2016，32（4）：624-626.
［4］	白毓，罗鸣，郝君.MR扩散加权成像联合T2WI对前列腺疾病诊断研究［J］.空军医学杂志，2017，33（1）：44-47.
［5］	Junghans RP，Ma Q，Rathore R，et al.Phase I trial of anti-PSMA designer CAR-T cells in prostate cancer：possible role for interacting interleukin 2-T cell pharmacodynamics as a determinant of clinical response［J］.Prostate，2016，76（14）：1257-1270.
［6］	章绪辉，梁文，全显跃，等.多模态 MRI技术对早期前列腺癌的应用研究［J］.中国临床医学影像杂志，2017，28（2）：116-119.
［7］	曹德宏，柳良仁，魏强，等.前列腺癌的治疗研究进展［J］.华西医学，2017，32（2）：277-281.
［8］	齐金蕾，王黎君，周脉耕，等.1990-2013年中国男性前列腺癌疾病负担分析［J］.中华流行病学杂志，2016，37（6）：778-782.
［9］	赵红超，祝恒成，吕胜启，等.低血清PSA型前列腺癌的回顾性研究［J］.临床泌尿外科杂志，2016，31（1）：59-61.
［10］	赖振汉，黄璐，杨舒萍，等.经直肠前列腺超声造影联合MRI靶向活检诊断前列腺癌［J］.中国超声医学杂志，2016，32（8）：724-728.
［11］	洪恽，陈军.经直肠超声造影辅助前列腺穿刺活检与前列腺系统穿刺活检在前列腺癌诊断中的比较研究［J］.中国性科学，2016，25（4）：24-26.
［12］	陆洋，葛尚，朱艳，等.DWI联合MRS对前列腺癌诊断的价值［J］.磁共振成像，2016，7（5）：327-331.
［13］	封小强，郭非，梁传栋，等.磁共振功能性成像诊断原发性颅脑恶性淋巴瘤［J］.河北医药，2015，37（9）：1374-1376.
［14］	宋志强，杜向东，茹荷燕，等.磁共振波谱分析在前列腺癌临床评估中的价值［J］.实用放射学杂志，2016，32（9）：1398-1401.
［15］	宫新扣.磁共振波谱在老年前列腺疾病诊断中的价值［J］.中国老年学杂志，2016，36（10）：2472-2473.
［16］	郭小鹏，成俊，王鹏.血清前列腺特异抗原、直肠指检联合磁共振波谱成像对前列腺癌的诊断价值［J］.中国实验诊断学，2016，20（3）：381-384.
［17］	郭会利，李培岭，张斌青，等.MRS与DWI联合成像在颈髓损伤诊断中的应用价值［J］.实用放射学杂志，2016，32（3）：335-338.
［18］	李文，李胜凯，林优，等.3.0T 磁共振 DWI、ADC、MRS 联合前列腺特异性抗原诊断前列腺癌效能分析［J］.实用医学杂志，2017，33（9）：1502-1505.
［19］	周玉末，余娜.磁共振MRS和DWI对前列腺中央腺体癌的影像诊断及临床应用价值分析［J］.医学理论与实践，2018，31（6）：883-885.
［20］	黄广，蔡德总.磁共振DWI与MRS成像在前列腺癌诊断中的价值探讨［J］.现代医用影像学，2017，26（1）：117-118.