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| Effect of Tianma Gouteng Decoction in the treatment of hypertension patients with the pattern of yin deficiency and yang hyperactivity |
| YANG Yu-hong1 SONG Ya-ling2 |
1. Department of Pharmacy, Wuhan Wudong Hospital, Hubei Province, Wuhan 430084, China；
2. Department of Pharmacy, Wuhan General Hospital of WISCO, Hubei Province, Wuhan 430080, China |
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Abstract Objective To study the effect of Tianma Gouteng Decoction in the treatment of hypertension patients with the pattern of yin deficiency and yang hyperactivity. Methods A total of 64 cases of hypertensive patients with the pattern of yin deficiency and yang hyperactivity admitted to Wuhan General Hospital of WISCO from October 5, 2017 to June 21, 2018 were selected as the research subjects, and they were divided into the control group and the observation group by dynamic random grouping method, with 32 cases in each group. Patients in the control group were treated with conventional method, and patients in the observation group were treated with Tianma Gouteng Decoction. Blood pressure and biochemical indicators (aldosterone, angiotensin II, renin) before and after treatment and adverse reactions in the two groups were compared. Results There was no significant difference in blood pressure between the two groups before treatment (P＞0.05). The diastolic blood pressure and systolic blood pressure of the two groups after treatment were lower than those before treatment, and the differences were statistically significant (P＜0.05). The diastolic blood pressure and systolic blood pressure after treatment of the observation group were (78.72±2.28) and (119.43±3.38) mmHg respectively, which were lower than those of the control group ([90.13±5.05], [135.37±2.26]) mmHg, and the differences were statistically significant (P＜0.05). There were no significant differences in biochemical indicators between the two groups before treatment (P＞0.05). The levels of aldosterone, angiotensin II and renin in the two groups after treatment were lower than those before treatment, and the differences were statistically significant (P＜0.05). The levels of aldosterone, angiotensin II and renin after treatment in the observation group were (280.11±3.74) ng/L, (108.14±5.25) ng/L,and (1.58±0.39) ng/ml respectively, which were lower than those in the control group ([309.87±4.04] ng/L, [119.70±4.38] ng/L, [4.11±0.55] ng/ml), and the differences were statistically significant (P＜0.05). The total incidence rate of adverse reactions was 3.13% in the observation group, which was significantly lower than the 21.88% in the control group, and the difference was statistically significant (P＜0.05). Conclusion The effect of Tianma Gouteng Decoction is remarkable in the treatment of hypertension patients with the pattern of yin deficiency and yang hyperactivity, which can effectively control the development of the disease.
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| [1] |
苗灵娟，李社芳，邢海燕，等.天麻钩藤饮加减治疗阴虚阳亢证高血压患者的临床疗效及机制[J].中国老年学杂志，2017，37（4）：851-853.
|
| [2] |
邓昭文.天麻钩藤饮加减治疗高血压病左室肥厚的疗效观察[J].中医药导报，2013，19（12）：66-67.
|
| [3] |
薛文海，吴佩华，倪爱华，等.天麻钩藤饮加减联合氯沙坦钾片治疗高血压及相关症状的疗效观察[J].中西医结合心脑血管病杂志，2017，15（20）：2598-2600.
|
| [4] |
王丽晓，黄飞.中西医结合治疗阴虚阳亢型老年高血压的临床效果探析[J].中外医疗，2016，35（35）：172-173.
|
| [5] |
樊云.天麻钩藤饮与厄贝沙坦-氢氯噻嗪片治疗阴虚阳亢型原发性高血压患者的临床疗效观察及偶测血压、动态血压对比评价[D].成都：成都中医药大学，2013.
|
| [6] |
王华杰.六味地黄丸合天麻钩藤饮加减治疗老年原发性高血压的疗效观察[J].中医临床研究，2016，8（18）：58-59.
|
| [7] |
孙海霞.天麻钩藤饮加减治疗高血压眩晕的临床效果观察[J].内蒙古中医药，2016，35（9）：36.
|
| [8] |
项学贵.天麻钩藤饮治疗阴虚阳亢证H 型高血压的临床观察[D].合肥：安徽中医药大学，2016.
|
| [9] |
周林，姚丽莉.加味天麻钩藤饮佐治H 型高血压病阴虚阳亢证25 例临床观察[J].浙江中医杂志，2017，52（10）：723-724.
|
| [10] |
夏柔娟.天麻钩藤饮联合杞菊地黄丸加减治疗高血压临床效果研究[J].临床医学研究与实践，2017，2（29）：109-110.
|
| [11] |
阮萍，廖华.天麻钩藤饮治疗阴虚阳亢型高血压50 例[J].解放军医药杂志，2016，28（5）：79-82.
|
| [12] |
梁海婷，林玲.天麻钩藤饮在阴虚阳亢型高血压治疗中的应用效果分析[J].内蒙古中医药，2017，36（15）：11-12.
|
| [13] |
沈军.天麻钩藤饮合杞菊地黄丸治疗阴虚阳亢型高血压病临床疗效[J].深圳中西医结合杂志，2017，27（14）：80-81.
|
| [14] |
廖慧玲.汪世强教授学术思想和临床经验总结（附“疏肝健脾”增效天麻钩藤饮治疗高血压病的临床研究）[D].成都：成都中医药大学，2016.
|
| [15] |
王艳辉.加味天麻钩藤饮联合西药对H 型高血压阴虚阳亢证的疗效观察[J].陕西中医，2016，37（8）：973-975.
|
|
|
|
