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| Application effect of general anesthesia combined with ultrasound-guided paravertebral nerve block on rapid recovery of thoracic-laparoscopic radical esophagectomy |
| LIN Xu-lin ZHANG Long-sheng ZHANG Huan-kai |
| Department of Anesthesiology, Jieyang People′s Hospital, Guangdong Province, Jieyang 522000, China |
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Abstract Objective To investigate the application effect of general anesthesia combined with ultrasound-guided paravertebral nerve block (USG-PVB) on rapid recovery of thoracic-laparoscopic radical esophagectomy (TLE). Methods Fifty patients who underwent TLE in our hospital from March to September 2018 were selected as the subjects, and randomly divided into observation group and control group, with 25 cases in each group. The USG-PVB was applied to the observation group under the induction of general anesthesia,and the control group only carrier out the induction of general anesthesia. The amount of vasoactive drugs and narcotic drugs in patients during surgery was observed and recorded. Cognitive function evaluation was performed using the simple intelligence state scale (MMSE) before and 2, 4,and 7 days after surgery. The pain visual analogue scale (VAS) score was observed at 1, 12, and 24 hours after surgery.Results The doses of sufentanil, remifentanil and propofol in the observation group were lower than those in the control group, the amount of phenylephrine was significantly higher than that of the control group (P＜0.05). There were no significant differences in MMSE scores between the two groups before and 7 days after surgery (P＞0.05). The MMSE scores of the observation group at 2 and 4 d after operation were significantly higher than those of the control group (P＜0.05). The VAS score of the observation group at 1, 12, 24 h after operation were significantly lower than thoes of the control group (P＜0.05). Conclusion General anesthesia combined with USG-PVB nerve block can reduce the amount of intraoperative anesthesia and vasoactive drugs, improve early cognitive dysfunction, and improve the quality of life of patients quickly. It is worthy of clinical application.
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