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Influential factors and prognosis of pathological complete remission of neoadjuvant therapy for breast cancer |
LI Shuai1MA Wen-jing2MA Jing1TANG Hui1 |
1.Clinical Inspection Center,People′s Hospital of Xinjiang Uygur Autonomous Region,Urumqi 830000,China;
2.Department of Clinical Laboratory,Traditional Chinese Medicine Hospital of Urumqi City in Xinjiang Uygur Autonomous Region,Urumqi830002,China |
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Abstract Objective To explore the influencing factors and prognosis of pathological complete remission of neoadjuvant therapy for breast cancer.Methods The clinical data of 150 patients with breast cancer admitted to People′s Hospital of Xinjiang Uygur Autonomous Region from June 12,2010 to June 12,2015 were retrospectively analyzed.All of them were women who received neoadjuvant chemotherapy.The clinical data,pathological data and follow-up data were collected and analyzed to explore the influencing factors and prognosis of pathological complete remission.Results Body mass,lactation time,chemotherapy cycle,tumor size,ER,PR,ER/PR and molecular typing were all single factors affecting the complete remission of neoadjuvant therapy.Complete remission has no significant effect on survival of breast cancer patients.Conclusion For breast cancer patients,body mass and ER are independent predictors of pathological complete remission of neoadjuvant therapy,and the pathological complete remission of neoadjuvant therapy has no significant impact on prognosis and survival of breast cancer patients.
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