PGⅠ、PGⅡ、G-17检测在胃癌及萎缩性胃炎诊断中的应用价值

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Abstract Objective To investigate the application value of PGⅠ,PGⅡand G-17 in the diagnosis of gastric cancer and atrophic gastritis.Methods A total of 120 patients with gastritis and gastric cancer admitted to our hospital from August 2016 to January 2018 were selected and divided into group A (40 patients with atrophic gastritis),group B(40 patients with superficial gastritis)and group C (40 patients with gastric cancer)according to the patient′s disease condition.The serum levels of PGⅠ,PGⅡand G-17 were analyzed.Results The levels of PGⅠ and PGⅡin group B were significantly higher than those in other two groups,and the levels of PGⅠ and PGⅡ in group A were significantly higher than those in group C,with significant difference(P＜0.05).The levels of G-17 in group C were significantly higher than those in other two groups,but the levels of PGR in group C were significantly lower than those in other two groups(P＜0.05).At the same time,the levels of PGⅠ and PGⅡ in Hp-positive patients were significantly higher than those in Hp-negative patients (P＜0.05).Conclusion PGⅠ,PGⅡ combined with G-17 can effectively reflect the pathological changes of gastric mucosa in patients with atrophic gastritis,and provide accurate data for the diagnosis of early gastric cancer,and provide a guarantee for clinical treatment.

Key words： PGⅠ PGⅡ G-17 Gastric cancer Atrophic gastritis Diagnostic

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	Articles by authors
	WU Feng
	ZHOU Zheng-qian
	LIU Zeng-yong
	SHUAI Shu-hao

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WU Feng,ZHOU Zheng-qian,LIU Zeng-yong, et al. Application value of PGⅠ,PGⅡand G-17 in the diagnosis of gastric cancer and atrophic gastritis[J]. 中国当代医药, 2019, 26(5): 86-88.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2019/V26/I5/86

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