MMP-9与支气管哮喘气道重塑的相关性及其临床应用研究进展

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Abstract The treatment of acute attack of bronchial asthma(asthma)is still based on its severity as an important reference and the severity of the disease was assessed by symptoms,signs,blood gas analysis and pulmonary function at onset in Guidelines for the prevention and treatment of bronchial asthma in China(2016).But there are certain limitations:the assessment of symptoms and signs is very subjective,and the prevalence of blood gas analysis and pulmonary function tests are not high in the primary hospital,and the pulmonary function tests are not practical in acute asthma attacks.Airway remodeling occurs early in the course of asthma and increases with the progression of the disease,which can reflect the severity of asthma.Matrix metalloproteinase-9(MMP-9)can be used as a biomarker for airway remodeling in asthma to assess asthma and airway remodeling.

Key words： Bronchial asthma Airway remodeling Matrix metalloproteinase-9 Assessment

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	YE Hong-wei
	LIANG Min-yong
	WANG Xiao-li
	WU Xiu-ming

Cite this article:

YE Hong-wei,LIANG Min-yong,WANG Xiao-li, et al. Correlation between MMP-9 and airway remodeling in bronchial asthma and its clinical application[J]. 中国当代医药, 2019, 26(2): 25-28.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2019/V26/I2/25

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