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Application evaluation of rapid on-site evaluation in endobronchial ultrasound-guided transbronchial needle aspiration |
ZHANG Lei1, YE Lian-hua1, CHEN Ying1, CHEN Ya1, JIN Ping2, YANG Cheng-gang2, TAN Hui1▲ |
1.The First Department of Thoracic Surgery,Yunnan Cancer Hospital,Yunnan Province,Kunming 650118,China;
2.Department of Pathology,Yunnan Cancer Hospital,Yunnan Province,Kunming 650118,China |
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Abstract Object To investigate the clinical value of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) combined with rapid on-site evaluation (ROSE) for enlarged hilar/mediastinal lymph nodes.Methods 104 patients with enlarged hilar/mediastinal lymph nodes by chest CT pointing out treated in Yunnan Cancer Hospital from June to December 2016 were randomly divided into the two groups,and they were given EBUS-TBNA,among them,there were 48 cases in on-site cytology group,while there were 56 cases in routine cytology group.Routine cell and histological findings were the gold standard.Results The diagnose rate in on-site cytology group and routine cytology group was 83.33% and 83.93% respectively,and the sonsistency of field cytology group with gold standard:kappa=0.883;the detection rate of malignant lymph nodes was 77.23% and 76.20% respectively,the time of puncture was (31.02±1.05) and (20.98±0.723)min respectively,the number of puncture was (1.57±0.24) times and (3.5±0.35) times,the incidence rate of puncture bleeding was 4.17%,5.37% respectively, secondary inspection rate was 0 and 3.57% respectively,and there was no statistical difference of above-mentioned data between the two groups (P>0.05).Conclusion EBUS-TBNA combined with ROSE in the diagnosis of enlarged hilar/mediastinal lymph nodes is effectively and reliable.The accuracy and gold standard is highly consistent.EBUS-TBNA combine with ROSE can reduce the incidence rate of complication such as puncture bleeding and secondary inspection rate,its safety is higher and it is better than EBUS-TBNA.
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Received: 15 May 2017
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[1] |
Griffin JP,Koch KA,Nelson JE, et al .Palliative care consultation,quality-of-life measurements,and bereavement for end-of-life care in patients with lung cancer:ACCP evidence-based clinical practice guide-lines (2nd edition)[J]. Chest,2007,132(Suppl 3): S404-S422.
|
[2] |
Wohlschlager J,Darwiche K,Ting S, et al .Rapid on-site evaluation (ROSE) in cytological diagnostics of pulmonary and mediastinal diseases[J].Pathologe,2012,33(4):308-315.
|
[3] |
Davenport RD.Rapid on-site evaluation of transbronchial aspirates[J].Chest,1990,98(1):59-61.
|
[4] |
Diette GB,White P Jr,Terry P, et al .Utility of on-site cytopathology assessment for bronchoscopic evaluation of lung masses and adenopathy[J].Chest,2000,117(4):1186-1190.
|
[5] |
Baram D,Garcia RB,Richman PS.Impact of rapid on-site cytologic evaluation during transbronchial needle aspiration[J].Chest,2005,128(2):869-875.
|
[6] |
Trisolini R,Cancellieri A,Tinelli C, et al .Rapid on-site evaluation of transbronchial aspirates in the diagnosis of hilar and mediastinal adenopathy:a randomized trial[J].Chest,2011,139(2) 395-401.
|
[7] |
Diacon AH,Schuurmans MM,Theron J, et al .Utility of rapid on-site evaluation of transbronchial needle aspirates[J].Respiration,2005,72(2):182-188.
|
[8] |
Yarmus L,Van der Kloot T,Lechtzin N, et al .Randomized prospective trial of the utility of rapid on-site evaluation of transbronchial needle aspirate specimens[J].J Bronchol Inter Pulmonol 2011,18(2):121-127.
|
[9] |
Chin RJ,McCain TW,Lucia MA, et al .Transbronchial needle aspiration in diagnosing and staging lung cancer: how many aspirates are needed?[J].Am J Respir Crit Care Med,2002,166(36): 377-381.
|
[10] |
Schenk DA,Bryan CL,Bower JH, et al .Transbronchial needle aspiration in the diagnosis of bronchogenic carcinoma [J].Chest,1987,92(1):83-85.
|
[13] |
李凯述,刘明涛,姜淑娟,等.经支气管镜针吸活检联合现场细胞学对肺癌诊断的临床价值[J].中国肺癌杂志,2014,17(3):215-220.
|
[11] |
Diacon AH,Schuurmans MM,Theron J, et al .Transbronchial needleaspirates:how many passes per target site? [J].Eur Respir J,2007,29(1):112-116.
|
[12] |
Butrynski JE,D′Adamo DR,Hornick JL, et al .Crizotinib in ALK-rearranged inflammatory myofibroblastic tumor[J].New Engl J Med,2010,363(18):1727-1733.
|
[14] |
Lee JE,Kim HY,Lim KY, et al .Endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of lung cancer[J].Lung Cancer,2010,70(1):51-56
|
[15] |
Yasufuku K,Pierre A,Darling G, et al .A prospective controlled trial of endobronchial ultrasound-guided transbronchial needle aspiration compared with mediastinoscopy for mediastinal lymph node staging of lung cancer[J].J Thorac Cardiovasc Surg,2011,142(6):1393-1400.
|
[16] |
Camidge DR,Bazhenova L,Salgia R, et al .First-in-human dose-finding study of the ALK/EGFR inhibitor AP26113 in patients with advanced malignancies:updated results[J].J Clin Oncol,2013,31(Suppl):8031.
|
[17] |
Gu P,Zhao YZ,Jiang LY, et al .Endobronchial ultrasound-guided transbronchial needle aspiration for staging of lung cancer:a systematic review and metaanalysis[J].Eur J Cancer,2009,45(8):1389-1396.
|
[18] |
Collins BT,Chen AC,Wang JF, et al .Improved laboratory resource utilization and patient care with the use of rapid on-site evaluation for endobronchial ultrasound fine-needle aspiration biopsy[J].Cancer Cytopathol,2013,121(10):544-551.
|
[19] |
Bonifazi M,Sediari M,Ferretti M, et al .The role of the pul monologist in rapid on-site cytologic evaluation of transbronchial needle aspiration:a prospective study[J].Chest J,2014,145(1):60-65.
|
|
|
|