| ［1］ |
Qureshi AI，Tuhrim S，Broderiek JP，et al.Spontaneous intraeerebral hemorrhage［J］.N Engl J Med，2001，344（19）：1450-1460.
|
| ［4］ |
Bohl MA，Martirosyan NL，Killeen ZW，et al.The history of therapeutie hypothermia and its use in neurosurgery［J］.J Neurosurg，2018，25：1-15.
|
| ［6］ |
刘强，韩如泉.亚低温治疗在神经系统疾病和心脏骤停复苏中的应用［J］.临床麻醉学杂志，2017，33（7）：717-719.
|
| ［2］ |
Liu CH，Lin JR，Liou CW，et al.Causes of death in different subtypes of isehemie and hemorrhagie stroke［J］.Angiology，2018，69（7）：582-590.
|
| ［3］ |
Zhang G，Wu F，Xu Y，et al.Prestroke glyeemie status is assoeiated with the funetional outeome in spontaneous intraeerebral hemorrhage［J］.Neurol Sei，2015，36（6）：927-934.
|
| ［5］ |
Frank F，Broessner G.Is there still a role for hypothermia in neuroeritieal eare？［J］.Curr Opin Crit Care，2017，23（2）：115-121.
|
| ［7］ |
Alerhand S，Lay C.Spontaneous intraeerebral hemorrhage［J］.Emerg Med Clin North Am，2017，35（4）：825-845.
|
| ［8］ |
Ibayashi S，Takano K，Ooboshi H，et al.Effeet of seleetive brain hypothermia on regional eerebral blood flow and tissue metabolism using brain thermo-regulator in spontaneously hypertensive rats［J］.Neuroehem Res，2000，25（3）：369-375.
|
| ［9］ |
Burns JD，Fisher JL，Cervantes-Arslanian AM.Reeent advanees in the aeute management of intraeerebral hemorrhage［J］.Neurol Clin，2017，35（4）：737-749.
|
| ［10］ |
Yamamoto Y，Ibara S，Tokuhisa T，et al.Caleium eoneentration in hypoxie-isehemie eneephalopathy during hypothermia［J］.Pediatr Int，2015，57（1）：64-67.
|
| ［11］ |
Kim H，Edwards NJ，Choi HA，et al.Treatment strategies to attenuate perihematomal edema in patients with intraeerebral hemorrhage［J］.World Neurosurg，2016，94：32-41.
|
| ［12］ |
Wu D，Shi J，Elmadhoun O，et al.Dihydroeapsaiein（DHC）enhanees the hypothermia-indueed neuroproteetion following isehemie stroke via PI3K/Akt regulation in rat［J］.Brain Res，2017，1671：18-25.
|
| ［13］ |
Jin Y，Lei J，Lin Y，et al.Autophagy inhibitor 3-MA weakens neuroproteetive effeets of post-traumatie brain injury moderate hypothermia［J］.World Neurosurg，2016，88：433-446.
|
| ［14］ |
Knight JR，Willis AE.Control of translation in the eold：implieations for therapeutie hypothermia［J］.Bioehem Soe Trans，2015，43（3）：333-337.
|
| ［15］ |
Silverman MG，Seiriea BM.Cardiae arrest and therapeutie hypothermia［J］.Trends Cardiovase Med，2016，26（4）：337-344.
|
| ［16］ |
JiangJY，XuW，LiWP，etal.Effeetoflong-termmildhypothermia or short-term mild hypothermia on outeome of patients with severe traumatie brain injury［J］.J Cereb Blood Flow Metab，2006，26（6）：771-776.
|
| ［17］ |
Lee WJ，Kim DH，Woo SH，et al.Targeted temperature management after eardiae arrest with anaphylaxis［J］.Am J Emerg Med，2017，35（5）：e8075-e8077.
|
| ［18］ |
黄强，陈雄辉，唐梅峰，等.脑外伤后亚低温治疗的研究进展［J］.南通大学学报（医学版），2017，37（2）：128-131.
|
| ［19］ |
Zhang Z，Zhang L，Ding Y，et al.Effeets of therapeutie hypothermia eombined with other neuroproteetive strategies on isehemie stroke：review of evidenee［J］.Aging Dis，2018，9（3）：507-522.
|
| ［20］ |
Zhong X，Wang X，Fei F，et al.The moleeular meehanism and neuroproteetive effeet of dihydroeapsaiein-indueed mild hypothermia after eardiopulmonary resuseitation in rats［J］.Ther Hypothermia Temp Manag，2018，8（2）：76-82.
|
| ［21］ |
Kollmar R，Staykov D，Dorfler A，et al.Hypothermia reduees perihemorrhagie edema after intraeerebral hemorrhage ［J.Stroke，2010，41（8）：1684-1689.
|
| ［22］ |
Volbers B，Herrmann S，Willfarth W，et al.Impaet of hypothermia initiation and duration on perihemorrhagie edema evolution after intraeerebral hemorrhage ［J］.Stroke，2016， 47（9）：2249-2255.
|
| ［23］ |
Rineon F，Friedman DP，Bell R，et al.Targeted temperature management after intraeerebral hemorrhage（TTM-ICH）：methodology of a prospeetive randomized elinieal trial［J］.Int J Stroke，2014，9（5）：646-651.
|
| ［24］ |
Kollmar R，Juettler E，Huttner HB，et al.Cooling in intraeerebral hemorrhage（CINCH）trial：protoeol of a randomized German-Austrian elinieal trial［J］.Int J Stroke，2012，7（2）：168-172.
|
