酪酸梭菌活菌散剂配合蓝光治疗新生儿高胆红素血症的效果

Abstract
Figure/Table
References (15)
Related Citation (15)

Download: PDF (0 KB) HTML (35 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To explore the feasibility of live clostridium butyricum Powder combined with blue light phototherapy treatment of neonatal with hyperbilirubinemia.Methods A total of 384 cases neonate with hyperbilirubinemia in our hospital from January 2016 to January 2018 were selected and randomly divided into the control group and the observation group according to random number table,192 cases in each group.Two groups of children were given the same dose of blue light irradiation treatment,observation group of children with blue light treatment and given Clostridium Butyricum powder 1.5 g/d,oral three times.The levels of bilirubin were measured before treatment and 1,4 and 7 days after treatment.The daily average decrease of bilirubin,the disappearance time of jaundice and the occurrence of adverse reactions were calculated and compared.Results There was no significant difference in bilirubin levels between the two groups before treatment(P＞0.05),after treatment,the bilirubin levels of the two groups were significantly lower than those before treatment(P＜0.05),the bilirubin level in the observation group after treatment for 4 and 7 d was significantly lower than that in the control group (P＜0.05).The average daily decrease of bilirubin in the observation group was significantly higher than that in the control group(P＜0.05),and the disappearance time of jaundice was significantly shorter than that in the control group (P＜0.05).The total incidence of adverse reactions in the observation group was significantly lower than that in the control group (P＜0.05).Conclusion Live Clostridium Butyricum Powder combined with blue light phototherapy in treatment of neonatal hyperbilirubinemia can improve the curative effect,shorten the treatment time and reduce adverse reactions.It is worth promoting in clinical practice.

Key words： Hyperbilirubinemia Neonate ')" href="#">Live Clostridium Butyricum Powder Blue light phototherapy

	Service

	E-mail this article Clostridium Butyricum Powder;Blue light phototherapy”. Please open it by linking:http://dangdaiyiyao.com/EN/abstract/abstract5856.shtml" name="neirong">
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	ZHAO Wei-kun
	HUANG Gui-hua

Cite this article:

ZHAO Wei-kun,HUANG Gui-hua. Efficacy of live Clostridium Butyricum powder combined with blue light phototherapy treatment of neonatal hyperbilirubinemia[J]. 中国当代医药, 2018, 25(29): 79-81.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I29/79

[1]	张士发，茅双根.新生儿黄疸的诊断与治疗[J].中华全科医学，2016，14（7）：1064-1065.
[2]	刘备，马国.新生儿黄疸的治疗药物研究进展[J].中国医院药学杂志，2015.35（16）：1515-1519.
[3]	唐春梅.新生儿黄疸蓝光治疗效果及不良反应探讨[J].中外医学研究，2015，13（33）：138-140.
[4]	姚建宏，李小艳，张新华，等.酪酸梭菌活菌散辅助治疗新生儿黄疸的随机多中心临床疗效观察[J].中国微生态学杂志，2016，28（10）：1178-1180.
[5]	中华医学会儿科学分会新生儿学组.新生儿高胆红素血症诊断和治疗专家共识[J].中华儿科杂志，2014，52（10）：745-748.
[6]	张晓蕊，曾超美，刘捷.强光疗治疗新生儿高胆红素血症的疗效及安全性[J].中国当代儿科杂志，2016，18（3）：195-200.
[7]	赵惠琴，张新华.新生儿高胆红素血症的病因分析和临床特点探讨[J].中国基层医药，2015，22（3）：380-382.
[8]	徐晓妮，王亚萍，王卫华，等.不同蓝光及照射方式治疗新生儿高胆红素血症的临床效果比较[J].医学综述，2016，22（13）：2660-2662.
[9]	覃安志，李强，郑志勇.不同蓝光照射方式对新生儿高胆红素血症的临床疗效分析[J].中国实用医刊，2015，42（9）：42-43.
[10]	王耀霜，杨曼，韩萍，等.新生儿黄疸应用多次短时蓝光照射对其血清胆红素浓度及不良反应的改善作用[J].临床和实验医学杂志，2017，16（10）：995-997.
[11]	李碧云，傅思武，王金丰.酪酸梭菌的研究进展[J].中国微生态学杂志，2013，25（1）：112-114.
[12]	刘欢，闫新荣.酪酸梭菌活菌散联合醒脾养儿颗粒治疗小儿消化不良性腹泻的疗效观察[J].中国医院用药评价与分析，2018，18（4）：471-472，475.
[13]	从欣，吴缨.茵栀黄颗粒、双歧杆菌四联活菌片及苯巴比妥片联合蓝光照射治疗早期新生儿黄疸疗效观察[J].中国中西医结合儿科学，2016，8（4）：429-431.
[14]	朱怀平.酪酸梭菌活菌胶囊联合甲硝唑治疗慢性末端回肠炎的临床研究[J].重庆医学，2018，47（18）：2492-2494.
[15]	樊爱民.新生儿黄疸蓝光治疗时间与不良反应的相关性分析[J].贵州医药，2016，40（5）：503-505.