肠道屏障功能与疾病发生关系的研究进展

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Abstract Intestinal barrier is one of the most important physical protection of the human beings.Abundant clinical and laboratorial researches reveal that destruction or debilitation of intestinal barrier may lead to bacterial translocation.Many physical symptoms such as endotoxin,D-lactate and diamine oxidase may change,which are related to vairous occurrence of diseases.Systemic inflammatory response syndrome (SIRS),even multiple organ dysfunction syndrome(MODS),may happen in serious situation.This paper elaborates the structure and function of the intestinal barrier,explain its mechanism of protection and inflammation.Diseaseas related with intestinal barrier are enumerated in detail.The review further shows that thedetection of intestinal barrier may play an important role in the prevention and paroxysm of serious diseases.

Key words： Intestinal mucosa Intestinal barrier Inflammatory reaction Bowel diseases Review

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	Articles by authors
	LI Rui
	LI Xiao-shuang
	GUI Chun-shuang
	REN Mei-ling
	WANG Jia-yi

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LI Rui,LI Xiao-shuang,GUI Chun-shuang, et al. Research progress of the relationship between intestinal barrier function and disease occurrence[J]. 中国当代医药, 2018, 25(23): 37-41.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I23/37

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