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Value study of different lung biopsy methods in the diagnosis of diffuse interstitial lung disease in elderly patients |
ZHAN Zi-e1 ZHAO Qiang-guang1 WU Sheng2 LI You-heng1▲ |
1.Department of Respiration,Shekou People′s Hospital of Nanshan District in Shenzhen City,Guangdong Province,Shenzhen 518067,China;2.Department of Respiration,Central Hospital of Kaiping City,Guangdong Province,Kaiping 529300,China |
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Abstract Objective To explore and analyze the clinical value of different lung biopsy methods in the diagnosis of diffuse interstitial lung disease in elderly patients.Methods A total of 117 patients with diffuse interstitial lung disease were selected in our hospital from March 2009 to September 2017.According to the patients′voluntary selection of lung biopsy,51 patients underwent fiberoptic bronchoscopic lung biopsy(TBLB)were selected as the TBLB group,35 patients in the puncture group underwent CT guided percutaneous lung biopsy,and 31 patients in the surgical lung biopsy group underwent video-assisted thoracoscopy or lung biopsy and small thoracotomy lung biopsy were performed.The diagnostic value,the incidence rate of postoperative complications,hospitalization time and operative cost of three lung biopsy methods were compared.Results The TBLB group clearly detected 34 cases(66.67%),the puncture group clearly detected 24 cases(68.57%),the surgical lung biopsy group was clearly detected in 30 cases(96.77%).The surgical lung biopsy group was significantly higher than that of the TBLB group and the puncture group(P<0.05),and there was no significant difference between the TBLB group and the puncture group (P>0.05).The incidence of postoperative complications in surgical lung biopsy group was significantly higher than that in the TBLB group and the puncture group (P<0.05).There was no significant difference in the incidence of postoperative complications between the TBLB group and the puncture group(P>0.05).Postoperative hospitalization time in the surgical lung biopsy group were significantly longer than that in the TBLB group and the puncture group,and biopsy cost in the surgical lung biopsy group was significantly higher than that in the TBLB group and the puncture group (P<0.05).There was no significant difference in postoperative hospitalization time and biopsy cost between the TBLB group and the puncture group (P>0.05).Conclusion For elderly patients with pulmonary diffuse interstitial lung disease,first consider transbronchial lung biopsy,and for the full clinical assessment is not clear diagnosis,or pathological type large biopsy patients,which can be taken open or video-assisted thoracoscopic lung biopsy.
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[1] |
管莎,黄宏,赵建平,等.透视引导下103例纤支镜肺活检临床分析[J].中国内镜杂志,2013,19(1):13-18.
|
[2] |
王昌国,曾大雄,雷伟,等.CT引导下经皮肺穿刺与超声引导下经支气管镜肺活检对肺周围型病变的诊断价值[J].中华结核和呼吸杂志,2015,38(12):897-900.
|
[3] |
Yaffe D,Koslow M,Haskiya H,et al.A novel technique for CT-guidedtransthoracicbiopsyoflunglesions:improvedbiopsy accuracy and safety[J].Eur Radiol,2015,25(11):3354-3360.
|
[4] |
Rotolo N,Imperatori A,Dominioni L,et al.Efficacy and safety of surgical lung biopsy for interstitial disease.Experience of 161 consecutive patients from a single institution in Italy[J].Sarcoidosis Vasc Diffuse Lung Dis,2015,32(3):251-258.
|
[5] |
董文,黄奕江,吴海洪,等.内科胸腔镜肺活检对弥漫性间质性肺疾病诊断价值及安全性分析[J].中国内镜杂志,2016,22(2):95-98.
|
[6] |
黄禹,任红岩,何碧芳,等.气管内超声非实时引导下经气管镜肺活检对肺周围型病变的诊断价值[J].中华结核和呼吸杂志,2013,36(1):12-16.
|
[7] |
Lim CS,Tan LE,Wang JY,et al.Risk factors of pneumothorax after CT-guided coaxial cutting needle lung biopsy through aerated versus nonaerated lung[J].J Vasc Interv Radiol,2014,25(8):1209-1217
|
[8] |
图门乌力吉,马忠森.特发性间质性肺炎经支气管镜肺活检组织中TGF-β1的表达及其意义[J].中国实验诊断学,2013,17(7):1219-1222.
|
[9] |
Chowdhry VK,Chowdhry AK,Goldman N,et al.Complications from computed tomography-guided core needle biopsy for patients receiving stereotactic body radiation therapy for earlystage lesions of the lung[J].Clin Lung Cancer,2014,15(4):302-306.
|
[10] |
Ishii H,Hiraki T,Gobara H,et al.Risk factors for systemic air embolism as a complication of percutaneous CT-guided lung biopsy:multicenter case-control study[J].Cardiovasc Intervent Radiol,2014,37(5):1312-1320.
|
[11] |
罗建光,杨东益,陈平,等.支气管镜肺活检在肺泡蛋白沉积症中的诊断价值[J].中南大学学报(医学版),2015,40(5):528-532.
|
[12] |
Dhooria S,Sehgal IS,Aggarwal AN,et al.Diagnostic yield and safety of cryoprobe transbronchial lung biopsy in diffuseparenchymallungdiseases:systematicreviewandMetaanalysis[J].Respir Care,2016,61(5):700-712.
|
[13] |
兰学立,李海潮,熊焰,等.经支气管镜肺活检在特发性间质性肺炎中的诊断价值[J].中国呼吸与危重监护杂志,2013,12(1):69-74.
|
[14] |
Chami HA,Faraj W,Yehia ZA,et al.Predictors of pneumothorax after CT-guided transthoracic needle lung biopsy:the role of quantitative CT[J].Clin Radiol,2015,70(12):1382-1387.
|
|
|
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