原发性醛固酮增多症致高血压脑出血3例诊治分析

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Abstract Primary aldosteronism refers to a syndrome that the adrenocortical lesions lead to increased aldosterone auto-secretion and renin-angiotensin system inhibition,together with hypertension with or without hypokalemia mainly characterized by plasma high aldosterone levels and low renin levels.It is a leading cause for secondary hypertension.The syndrome can be screened by using plasma aldosterone/renin ratio(ARR),adrenal ultrasound,adrenal computed tomography(CT)and enhanced,adrenal magnetic resonance imaging(MRI).The key treatment is actively control of blood pressure and actively potassium supplementation to correct electrolyte imbalances.For aldosteronoma patients,the preferred therapy is total unilateral adrenalectomy or tumor resection under laparoscope.This paper analyzed and summarized the diagnosis and treatment of three patients with hypertensive cerebral hemorrhage caused by primary aldosteronism in order to intensify awareness of the disease,enhance the clinical experience,and guide the clinical diagnosis and treatment.

Key words： Primary aldosteronism Aldosteronoma Secondary hypertension Cerebral hemorrhage

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	DAI Pei
	SONG Gui-qin

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DAI Pei,SONG Gui-qin. Analysis of diagnosis and treatment of hypertensive cerebral hemorrhage caused by primary aldosteronism in three cases[J]. 中国当代医药, 2018, 25(18): 153-157.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I18/153

[1]	Funder JW，Carey RM，Mantero F，et al.The management of primary aldosteronism：case detection，diagnosis，and treatment：an endocrine society clinical practice guideline[J].J Clin Endocrinol Metab，2016，101（5）：1889-1916.
[2]	Rayner B.Primary aldosteronism and aldosterone-associated hypertension[J].J Clin Pathol，2008， 61（7）： 825-831.
[3]	张洁，吴剑敏，徐国焱，等.原发性醛固酮增多症致脑出血1 例[J].中华高血压杂志，2014，22（10）：995-997.
[4]	Young WF Jr.Minireview：primary aldosteronism-changing concepts in diagnosis and treatment[J].Endocrinology，2003，144（6）：2208-2213.
[5]	Calhoun DA，Nishiaka MK，Zaman MA，et al.Hyperaldosteronism among black and white subjects with resistant hypertension[J].Hypertension，2002，40（6）： 892-896.
[6]	Galati SJ.Primary aldosteronism：challenges in diagnosis and management[J].EndocrinolMetabClinNorthAm，2015，44（2）：355-369.
[8]	杨淑敏，李启富.2016年美国原发性醛固酮增多症指南解读[J].重庆医科大学学报，2016，41（11）：1177-1179.
[9]	Stowasser M，Ahmed AH，Pimenta E，et al.Factors affecting the aldosterone/renin ratio[J].Horm Metab Res，2012，44（3）：170-176.
[11]	Young WF.Primary aldosteronism：renaissance of a syndrome[J].Clin Endocrinol（Oxf），2007，66（5）：607-618.
[12]	邓助朋，陈宁，李辉华，等.中青年高血压患者肾上腺影像学检查的临床意义[J].中国医药导刊，2013，15（S）：22-23.
[7]	Sawada K，Maehara T，Inaji M，et al.Case of ruptured multiple cerebral aneurysms associated with primary aldosteronism[J].No Shinkei Geka，2010，38（4）： 347-351.
[10]	Ducher M，Mounier-Vehier C，Baguet JP，et al.Aldosteroneto-renin ratio for diagnosing aldosterone-producing adenoma：a multicenter study[J].Arch Cardiovasc Dis，2012，105（12）：623-630.
[13]	廖勇，邓春颖.对比B超和HRCT在原发性醛固酮增多症定位及分型诊断中的应用价值[J].中国医学创新，2017，14（30）：47-50.
[14]	朱理敏，龚艳春，林伯贤，等.原发性醛固酮增多症患者药物治疗随访分析[J].中华高血压杂志，2013，21（6）：531-535.
[15]	Zhang X，Zhu Z，Xu T，et al.Factors affecting complete hypertension cure after adrenalectomy for aldosterone-producing adenoma：outcomes in a large series[J].Urol Int，2013，90（4）：430-434.
[16]	Rossi GP，Bernini G，Caliumi C，et al.PAPY Study Investigators.A prospective study of the prevalence of primary aldosteronism in 1，125 hypertensive patients[J].Am Coll Cardiol，2006，48（11）：2293-2300.
[17]	Mulatero P，Stowasser M，Loh KC，et al.Increased diagnosis of primary aldosteronism，including surgically correctable forms，in centers from five continents[J].Clin Endocrinol Metab，2004，89（3）：1045-1050.
[18]	Rossi GP，Bernini G，Caliumi C，et al.A prospective study of the prevalence of primary aldosteronism in 1 125 hypertensive patients[J].J Am Coll Cardiol，2006，48（11）：2293-2300.
[19]	张艳丽，姜一农，刘莹.原发性醛固酮增多症重度低血钾致多脏器损害 1 例[J].中国高血压杂志，2015，23（7）：695-697.
[20]	中华医学会内分泌学会肾上腺学组.原发性醛固酮增多症诊断治疗的专家共识[J].中华内分泌代谢杂志，2016，32（3）：188-195.
[21]	Tomaschitz A，Pilz S.Aldosterone to renin ratio—a reliable screening tool for primary aldosteronism[J].Horm Metab Res，2010，42（6）：382-391.