戈舍瑞林与米非司酮在腹腔镜手术治疗巧克力囊肿中的应用效果

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Abstract ObjectiveTo explore the clinical effect of laparoscopic surgery combined with Goserelin and Mifepristonein treatment of chocolate cyst of the ovary.MethodsFrom March 2013 to March 2015,88 patientswith chocolate cystwere randomly divided into Goserelin group and Mifepristone group,44 cases in each group.All the cases in the two groups were treated by laparoscopic surgery,then the patients in Goserelin group were treated by Gestrinone,the patients in Mifepristone group were treated by Mifepristone.The serum levels of follicle stimulating hormone(FSH),luteinizing hormone(LH)and estradiol(E2)before and after therapy,the clinical effects,symptom improvement,infertility rate,recurrence rates,and pregnancy rates of the two groups were compared.ResultsThere was no statistically significant difference in the levels of serum FSH,LH before and after treatment between the two groups(P＞0.05).Therewas no statistically significant difference in the levels of serum E2before treatment,but the levels of serum E2level in Goserelin group was statistically significantly lower than that in Mifepristone group(P＜0.05),after treatment,the clinical symptoms such as algopareunia and dysmenorrhea improved obviously after treatment in the two groups,but there was no statistically significant difference in the improvement between the two groups.There was no significant difference in the infertility rate between the two groups before treatment(P＞0.05).The total effective rates,recurrence rates,and pregnancy rates were 90.9%,11.4%,62.5%in Goserelin group and 77.3%,27.3%,43.5%in Mifepristone group,respectively,there were statistically significant differences between the two groups(P＜0.05).ConclusionThere are somany advantages to treat chocolate cystwith laparoscopic surgery combined with Goserelin,such as significant clinical effect and low recurrence rate.It isworthy for extending in clinic.

Key words： Chocolate cyst Laparoscopic surgery Goserelin Mifepristone Recurrence rate Pregnancy rate

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WEILi-fen. Effect of Goserelin and M ifepristone in treatment of chocolate cyst by laparoscopy[J]. 中国当代医药, 2018, 25(16): 114-117.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I16/114

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