腹腔镜根治术与开腹根治术治疗老年大肠癌患者的临床对比研究

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Abstract Objective To investigate the clinical efficacy of laparoscopic radical colectomy and open radical colorectal resection for senile patients with colorectal cancer.Methods A total of 112 senile patients with colorectal cancer enrolled in the First Affiliated Hospital of Guangdong Pharmaceutical University from June 2010 to June 2013 were selected as research objects.The patients were divided into laparoscopic group (n=57)and laparotomy group (n=55),according to different operation methods.The following indexes of the two groups were compared：operation time,number of resected lymph nodes,intraoperative bleeding loss,postoperative ambulation time,gastrointestinal function recovery time,complications(incision fat liquefaction and infection,anastomotic bleeding,anastomotic fistula,ileus,deep vein thrombosis,cerebral infarction and pulmonary infection incidence rate and total hospitalization time.The survival rate and recurrence rate of the two groups were compared at 1,2 and 3 years after operations.Results There was no significant difference in the operation time and the number of resected lymph nodes in the two groups(P＞0.05).The amount of bleeding in the laparoscopic group was significantly reduced(P＜0.05).The postoperative ambulation time,gastrointestinal function recovery time and total hospitalization time in the laparoscopic group was significantly shortened(P＜0.05).Postoperative complications such as incision fat liquefaction and infection,anastomotic bleeding,anastomotic fistula,adhesive ileus,deep vein thrombosis,cerebral infarction and pulmonary infection rate of the laparoscopic group were lower than those in the laparotomy group,and the differences were statistically significant(P＜0.05).The survival rates at 1,2,and 3 years after the operation were 100.00%,92.89%and 91.22%in the laparoscopic group and 98.18%,92.72%and 90.90%in the laparotomy group.The recurrence rates at 1，2，and 3 years after the operation were 3.50%，5.26%and 8.77%in the laparoscopic group,and 3.63%,5.45%and 10.90%in the laparotomy group.There was no significant difference in the survival rate and recurrence rate between the two groups(P＞0.05).Conclusion Laparoscopic radical surgery for elderly patients with colorectal cancer is safe and feasible,and its clinical effect is superior to traditional open radical surgery,and has a good application prospect.

Key words： Laparoscopic radical colectomy Open radical colorectal resection Colorectal cancer

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	CHEN Dan
	ZHANG Wei-bin
	WU Min-hua

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CHEN Dan,ZHANG Wei-bin,WU Min-hua. A comparative study of laparoscopic radical colectomy and open radical colorectal resection for senile patients with colorectal cancer[J]. 中国当代医药, 2018, 25(11): 71-74.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I11/71

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