阿奇霉素治疗小儿支原体肺炎的临床效果观察

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Abstract Objective To investigate clinical efficacy of Azithromycin in the treatment of 31 cases of Mycoplasma pneumonia in children.Methods A total of 62 children with Mycoplasma pneumonia were collected from June 2014 to June 2017 in our hospital and were randomly divided into control group(n=31)and observation group(n=31).The two groups were given symptomatic treatment.On the basis of treatment,the control group was treated with Erythromycin,while the observation group was treated with Azithromycin.The therapeutic effects of the two groups were compared.Results①The fever time,cough time and rale time in the observation group were shorter than those in the control group(P＜0.05).②The total effective rate of the observation group was 94.5%,which was significantly higher than 70.9%of the control group(P＜0.05).③The adverse reaction rate of the observation group was 12.9%,which was significantly lower than 35.4%of the control group,the differences were statistically significant(P＜0.05).Conclusion In the treatment of children with Mycoplasma pneumonia,Azithromycin can effectively improve the patient′s clinical symptoms and signs,treatment effect is good,and adverse reaction is less.It is an ideal treatment drug.

Key words： Mycoplasma pneumonia in children Azithromycin Erythromycin Clinical efficacy

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	OU Qi

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OU Qi. Clinical efficacy of Azithromycin in the treatment of Mycoplasma pneumonia in children[J]. 中国当代医药, 2018, 25(13): 160-162.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I13/160

[1]	中华医学会儿科学分会呼吸学组，《中华实用儿科临床杂志》编辑委员会.儿童肺炎支原体肺炎诊治专家共识（2015年版）[J].中华实用儿科临床杂志，2015，30（17）：1304-1308.
[2]	Chang HY，Chang LY，Shao PL，et al.Comparison of realtime polymerase chain reaction and serological tests for the confirmation of Mycoplasma pneumoniae infection in children with clinical diagnosis of atypical pneumonia[J].J Microbiol Immunol Infect，2014，47（2）：137-144.
[3]	杨海军.小儿肺炎支原体肺炎85例临床分析[J].中国当代医药，2015，23（25）：93-96.
[4]	卢仕仰，黄从付，刘巧红，等.头孢他定钠联合阿奇霉素治疗小儿肺炎支原体肺炎的临床效果[J].中国当代医药，2016，23（5）：59-60.
[5]	Aizawa Y，Oishi T，Tsukano S，et al.Clinical utility of loopmediated isothermal amplification for rapid diagnosis of Mycoplasma pneumoniae in children[J].J Med Microbiol，2014，63（2）：248-251.
[6]	梅淑芬，金海丽，王孙尧，等.儿童难治性肺炎支原体肺炎临床特点分析[J].中国中西医结合急救杂志，2017，24（2）：129-132.
[7]	马前进.小儿支原体肺炎54例临床治疗[J].中国伤残医学，2015，12（6）：141-142.
[8]	顾红，朱雪凤，杨海燕，等.护理干预对红霉素序贯治疗小儿支原体肺炎疗效的影响[J].江苏卫生事业管理，2017，28（3）：125-126.
[9]	王艳萍，余伟智，刘贤茂，等.阿奇霉素联合痰热清对小儿支原体肺炎的治疗价值评析[J].泰山医学院学报，2016，37（12）：1407-1408.
[10]	吴伟波，陈倩.阿奇霉素联合特步他林雾化吸入治疗小儿支原体肺炎的临床疗效[J].中国临床药理学杂志，2014，12（6）：475-477.
[11]	王素霞，王静，任常军，等.阿奇霉素序贯疗法治疗小儿支原体肺炎的疗效和安全性分析[J].中国生化药物杂志，2014，11（5）：133-134.
[12]	李小莉，喻鸿绒，郭纪元，等.希舒美干混悬剂与阿奇霉素序贯治疗小儿支原体肺炎260例对比观察[J].陕西医学杂志，2015，12（9）：1243-1244.
[13]	刘永焕，翁艳心，许毅虹，等.红霉素和阿奇霉素治疗小儿肺炎支原体肺炎疗效对比[J].当代医学，2014，18（17）：137-138.
[14]	龚睿.阿奇霉素治疗小儿支原体肺炎的效果观察和安全性分析[J].中国微生态学杂志，2015，27（5）：571-573.
[15]	Thompson AM，Thomas SE，Schafers SJ，et al.The role of azithromycin in healthcare-associated pneumonia treatment[J].J Clin Pharm Ther，2015，（5）：517-524.
[17]	雷兴丽，兰志建，徐军，等.盐酸溴己新联合阿奇霉素治疗小儿支原体肺炎的疗效及对患儿血清炎症因子水平的影响[J].中国生化药物杂志，2017，37（1）：248-250.
[18]	马晓，梁瑾，吕润泽，等.阿奇霉素联合孟鲁司特钠治疗小儿支原体肺炎的疗效及对C反应蛋白水平的影响[J].中国医院用药评价与分析，2017，17（7）：900-901.
[16]	Lee G，Gabin H，Fawaz F，et al.Azithromycin is not associated with QT prolongation in hospitalized patients with community-acquired pneumonia[J].Pharmacoepidemiol Drug Saf，2015，（10）：1042-1048.