左氧氟沙星联合常规抗痨治疗艾滋病合并肺结核的效果研究

Abstract
Figure/Table
References (17)
Related Citation (15)

Download: PDF (0 KB) HTML (37 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the clinical effect of Levofloxacin combined with conventional anti-tuberculosis therapy on AIDS patients with pulmonary tuberculosis.Methods A total of 42 patients with HIV-positive pulmonary tuberculosis admitted to Yangjiang Public Health Hospital from January 2014 to December 2016 were randomly divided into control group and treatment group,21 cases in each group.The control group received conventional anti-tuberculosis therapy.The treatment group was treated with Levofloxacin and routine anti-tuberculosis treatment,the clinical effect of two groups of patients were analyzed and compared.Results The total effective rate of the treatment group was significantly higher than that of the control group(P＜0.05);the sputum negative conversion rate of the treatment group was higher than that of the control group(P＜0.05);the treatment group improved MRC dyspnea score,1 seconds rate,6-minute walk distance were significantly higher than that in the control group,indicated that the respiratory function of the treatment group was better than that of the control group,the differences were statistically significant(P＜0.05).The incidence of adverse reactions in the treatment group was 42.86%,the incidence of adverse reactions in the control group was 38.10%.There was no significant difference in the incidence of adverse reactions between the two groups (P＞0.05).Conclusion Levofloxacin combined with conventional anti-tuberculosis therapy in patients with AIDS-associated pulmonary tuberculosis is not only effective,but also has a small adverse reaction，and can be used as a new generation of anti-TB drugs,especially in the treatment of tuberculosis in special populations.

Key words： Levofloxacin Conventional anti-tuberculosis treatment AIDS Tuberculosis Effect

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	CHEN Ting-xian
	CHEN Yong-yi
	HUANG Xiu-huo
	DAI Fen

Cite this article:

CHEN Ting-xian,CHEN Yong-yi,HUANG Xiu-huo, et al. Effect study of Levofloxacin combined with conventional anti-tuberculosis therapy on AIDS complicated with tuberculosis[J]. 中国当代医药, 2018, 25(13): 35-37转41.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I13/35

[1]	卡丽毕努尔·力提甫，林栋羚，宋江美，等.督促干预对艾滋病患者肺结核感染的治疗效果分析[J].中华医院感染学杂志，2017，27（17）：4041-4044.
[2]	刘敏，李奇穗，谭顺，等.艾滋病合并结核病患者结核分枝杆菌原发耐药的回顾性研究[J].中华传染病杂志，2017，35（5）：278-281.
[3]	李卫鸿，刚永桂，刘明，等.左氧氟沙星、胸腺五肽和四君子汤联合治疗重症肺结核的机制研究[J].中国中西医结合急救杂志，2017，24（1）：44-48.
[4]	殷继国，何卫华，练祖银，等.湖北省随州市艾滋病/肺结核病双重感染患者抗结核治疗与抗病毒治疗效果分析[J].中国预防医学杂志，2015，16（3）：171-174.
[5]	李洪智，张翰明，武艳霞.抗结核方案联合薄芝糖肽注射液治疗艾滋病合并继发性肺结核疗效观察[J].中国实用医刊，2017，44（5）：109-110.
[6]	陈焯彬，梁浩.肺结核合并艾滋病患者抗结核治疗的转归及危险因素分析[J].中华实用诊断与治疗杂志，2016，30（11）：1080-1081.
[7]	刘幸，欧阳兵，杜映荣，等.内消瘰疬丸联合左氧氟沙星治疗耐多药肺结核的临床疗效分析[J].中国医药导刊，2017，19（8）：787-790.
[8]	袁一加，龚唯.左氧氟沙星联合抗结核方案治疗肺结核临床效果[J].中国现代医生，2016，54（11）：76-78.
[9]	童维佳，王永庆.阿莫西林/克拉维酸钾联合左氧氟沙星治疗耐多药肺结核的临床效果[J].临床肺科杂志，2015，20（9）：1602-1604.
[10]	陆霓虹，汪亚玲，欧阳兵，等.抗痨补肺汤联合化疗治疗耐多药肺结核随机平行对照研究[J].实用中医内科杂志，2015，29（10）：98-100.
[11]	刘幸，欧阳兵，冷艳朵，等.结核丸与左氧氟沙星等抗结核药物联用对耐多药肺结核患者的疗效分析[J].抗感染药学，2017，14（3）：511-514.
[12]	徐永，胡静巧.左氧氟沙星辅助治疗127例耐多药肺结核临床疗效研究[J].中国地方病防治杂志，2015，30（4）：318.
[13]	陈亮，郑俊，陈郁明，等.左氧氟沙星联合利福布汀治疗耐多药肺结核的临床效果研究[J].北方药学，2016，13（2）：48-49.
[14]	王罛.不同抗结核方案治疗艾滋病合并继发性肺结核感染的效果分析[J].医学美学美容，2015，23（2）：122-123.
[15]	王飞，康定理，胡秀琼，等.硫普罗宁联合拉米夫定在肺结核合并慢性乙型肝炎治疗中的作用[J].中国药房，2016，27（29）：4112-4115.
[16]	黄培生，余复火，刘桂芬.对氨基水杨酸异烟肼联合左氧氟沙星治疗复治菌阳尘肺结核临床疗效研究[J].实用心脑肺血管病杂志，2015，12（3）：25-26.
[17]	徐俊彦，薛卫.常规治疗加用利福布汀联合莫西沙星治疗40例多药耐药肺结核患者的疗效观察[J].世界临床药物，2015，36（4）：264-268.