麻醉药导致术后认知功能障碍的海马内机制研究进展

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Abstract Preclinical investigations demonstrated that postoperative memory functions may be influenced by anesthetics,especially the spatial memory and learning functions of hippocampus.Different anesthetics may have different pathways and outcomes on postoperative cognitive functions.This review discuss the recent progress of anesthetics influence on postoperative hippocampal cognitive dysfunction,mainly in the pathways of structure basics,neuroinflammation,neuronal apoptosis,nerve conduction and blood brain barrier.

Key words： Anesthetics Postoperative cognition Hippocampus Neuroinflammation

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	Articles by authors
	WANG Chen
	ZHANG Hong
	SHEN Hao

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WANG Chen,ZHANG Hong,SHEN Hao. The role of general anesthetics and the mechanisms of hippocampal functions in the postoperative cognitive dysfunction[J]. 中国当代医药, 2018, 25(13): 20-23.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I13/20

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