胃炎康胶囊辅助治疗胆汁反流性胃炎的效果及安全性

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Abstract Objective To explore the clinical efficacy and safety of Weiyanang Capsule in the treatment of bile reflux esophagitis.Methods A total of 120 patients with bile reflux gastritis treateed in our hospital from May 2015 to May 2017 were selected as subjects and divided into the observation group and the control group by dynamic random grouping method,60 cases in each group.The control group was treated with Hydrotalcite Tablets,while the observation group was given the auxiliary treatment of Weiyankang Capsule on the basis of the control group.The clinical effects were observed between the two groups.And the clinical symptom scores,gastric acid secretion,astric juice cholic acid content,plasma motilin (MTL)and serum vasoactive intestinal peptide (VIP)before and after treatment were compared between the two groups.Results The total effective rate of the observation group(96.7%)was significantly higher than that in the control group of 85.0%,the difference was statistically significant(P＜0.05).Before treatment,there was no significant difference in symptom score,gastric acid secretion,cholic acid in gastric juice,serum VIP and plasma MTL between the two groups(P＞0.05).The symptom score,gastric acid secretion,gastric acid and serum VIP after treament of two groups were significantly lower than before treatment,the differences were statistically significant(P＜0.05).And after treatment,these indexs of the observation group were lower than those of the control group,the differences were statistically significant(P＜0.05).After treatment,the plasma MTL after treament of two groups were significantly higher than before treatment(P＜0.05),and the plasma MTL in the observation group was significantly higher than that in the control group,the differences were statistically significant(P＜0.05).There were none adverse drug reactions in the two groups.ConclusionWeiyankang Capsule is an effective adjuvant therapy for bile reflux gastritis.It can significantly improve the clinical effective rate,improve various examination indexes,and is highly safe.It is worthy of popularization and application.

Key words： Weiyankang Capsule Bile reflux gastritis Motilin Vasoactive intestinal peptide

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DAI Xiao-min. The efficacy and safety of Weiyankang Capsule in the treatment of bile reflux gastritis[J]. 中国当代医药, 2018, 25(12): 88-91.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I12/88

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