红霉素和阿奇霉素序贯疗法与单用阿奇霉素治疗支原体肺炎患儿的效果对比

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Abstract Objective To explore the effect of Erythromycin and Azithromycin sequential therapy in the treatment of mycoplasma pneumonia.Methods Altogether 200 cases of children with mycoplasma pneumonia who were treated in our hospital from September 2015 to August 2017 were selected as subjects and randomly divided into two groups,100 cases in each group.The children of two groups were both given conventional symptomatic treatment,the children in the control group were treated with Azithromycin alone,while the children in the observation group were treated with Erythromycin and Azithromycin sequential therapy.The total effective rate,adverse reaction rate,treatment time and hospitalization duration were compared between the two groups.Results After treatment,the total effective rate in the observation group(97.0%)was higher than that in the control group(88.0%),and the difference was statistically significant(P＜0.05).During the treatment,the total incidence of adverse reactions in the observation group (4.0%)was lower than that in the control group(13.0%),and the difference was statistically significant(P＜0.05).The treatment time and hospitalization duration of the children in the observation group were shorter than those in the control group,and the differences were statistically significant(P＜0.05).ConclusionThe sequential therapy of Erythromycin and Azithromycin can help to reduce the adverse drug reactions of children with mycoplasma pneumonia,shorten the treatment time,and make the patients recover early.

Key words： Erythromycin Azithromycin Sequential therapy Mycoplasma pneumonia

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	Articles by authors
	MA Xing-wei
	WU Wei-sen
	CHEN Pei-qun
	MA Ya-hong
	LIN Ni-yang

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MA Xing-wei,WU Wei-sen,CHEN Pei-qun, et al. Effect comparison of the Erythromycin,Azithromycin sequential therapy and Azithromycin alone in the treatment of mycoplasma pneumonia in children[J]. 中国当代医药, 2018, 25(9): 97-99.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I9/97

[1]	王磊，魏彬.血清超敏C反应蛋白水平对阿奇霉素治疗儿童支原体肺炎疗效的影响[J].医学研究杂志，2017，46（9）：181-184.
[2]	陈华，陈玲，潘安直，等.普米克令舒雾化吸入对支原体肺炎患儿血清 sICAM-1、SP-A、IGF-1水平的影响[J].中国生化药物杂志，2017，37（3）：222-224.
[3]	王素霞，王静，任常军，等.阿奇霉素序贯疗法治疗小儿支原体肺炎的疗效和安全性分析[J].中国生化药物杂志，2014，34（5）：133-134，138.
[4]	Cassady JR，Jaffe N，Filler RM.The increasing importance of radiation therapy in the improved prognosis of children with Wilms′tumor[J].Cancer，1997，39（S2）：825-829.
[5]	Marina NM，Pratt CB，Rao BN，et al.Improved prognosis of children with osteosarcoma metastatic to the lung （s） at the time of diagnosis[J].Cancer，1992，70（11）：2722-2727.
[6]	朱玫，吴惠兰.两种大环内酯类抗生素治疗小儿支原体肺炎的成本——效果分析[J].临床药物治疗杂志，2016，14（3）：67-69.
[7]	廖洪彬，文启芹，明怀志，等.阿奇霉素联合红霉素对支原体肺炎患儿临床疗效研究[J].辽宁医学院学报，2016，37（1）：29-31.
[8]	钱发英，吴海燕，童欣，等.阿奇霉素序贯疗法治疗小儿支原体肺炎疗效观察[J].中国基层医药，2015，22（13）：2013-2016.
[9]	曾国庆，刘国英，陈瑞林，等.阿奇霉素序贯疗法治疗小儿肺炎支原体肺炎疗效观察[J].中国中西医结合儿科学，2016，8（1）：46-48.
[10]	徐良斌.阿奇霉素联合红霉素治疗小儿支原体肺炎80例疗效评价[J].中国药业，2015，24（23）：67-68.
[11]	刘晓燕，王曼知.阿奇霉素与红霉素对支原体肺炎患儿血清 hs-CRP、TNF-α、IL-8的影响和治疗效果比较[J].湖南师范大学学报（医学版），2017，14（3）：60-63.
[12]	吴进.阿奇霉素与红霉素治疗儿童支原体肺炎的临床疗效及安全性比较[J].中国药物经济学，2016，11（3）：47-49.
[13]	刘珍莲，张德明，陈玉婷，等.阿奇霉素和红霉素序贯疗法治疗小儿支原体肺炎临床效果及并发症影响效果[J].北方药学，2016，13（3）：131-132.
[14]	刘东锋.红霉素与阿奇霉素序贯疗法在小儿肺炎支原体肺炎中的临床应用[J].中国卫生标准管理，2016，7（10）：90-92.
[15]	陈嘉慧，印根权，余嘉璐，等.红霉素与阿奇霉素治疗小儿肺炎支原体肺炎的临床研究[J].中国临床药理学杂志，2015，31（8）：587-589.