压力释放通气模式与肺保护性通气治疗急性呼吸窘迫综合征的对比研究

Abstract
Figure/Table
References (15)
Related Citation (15)

Download: PDF (0 KB) HTML (30 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To explore the effects of airway pressure release ventilation(APRV)and lung protective ventilation(SIMV)on acute respiratory distress syndrome.Methods 94 patients with acute respiratory distress syndrome admitted to our hospital from November 2016 to November 2017 were selected as the research subject,and were divided into two groups(n=47)according to the random number table method.Pulmonary protective ventilation was performed in the SIMV group and airway pressure release ventilation was applied in the APRV group.The arterial blood gas index,airway mechanics,hemodynamics and lung injury were compared between the two groups before ventilation and 2 days after ventilation.Results There was no significant difference in PaO2/FiO2,ELWI,Ppeak and Pmean between the two groups before ventilation (P＞0.05).After ventilation,however,the PaO2/FiO2in the SIMV group was shown to be lower than that in the APRV group,while the ELWI,Ppeak and Pmean were higher than that in the APRV group,the differences were statistically significant(P＜0.05).There was no significant difference in HR,CVP,MAP and Murray score between the two groups before ventilation(P＞0.05).After 2 days of ventilation,the HRV,CVP and Murray scores in the SIMV group were shown to be higher than those in the APRV group,and the MAP was lower than that in the APRV group,the differences were statistically significant(P＜0.05).Conclusion Compared with SIMV,APRV is more effective in the treatment of patients with acute respiratory distress syndrome,which is beneficial to their respiratory function and lung recruitment.It can also improve the hemodynamics of the patients and is better for their recovery.

Key words： Acute respiratory distress syndrome Airway pressure release ventilation Pulmonary protective ventilation Lung injury Hemodynamics

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	PAN Jian
	MA Jun-wu
	DENG Xiu-fan
	HUANG Xiao-ming

Cite this article:

PAN Jian,MA Jun-wu,DENG Xiu-fan, et al. Comparative study on pressure release ventilation and pulmonary protective ventilation for acute respiratory distress syndrome[J]. 中国当代医药, 2018, 25(9): 43-45.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I9/43

[1]	Luo J，Yu H，Hu YH，et al.Early identification of patients at risk for acute respiratory distress syndrome among severe pneumonia： a retrospective cohort study[J].J Thorac Dis，2017，9（10）：3979-3995.
[2]	Park J，Pabon M，Choi AMK，et al.Plasma surfactant protein-D as a diagnostic biomarker for acute respiratory distress syndrome：validation in US and Korean cohorts[J].BMC Pulm Med，2017，17（1）：204.
[3]	宋邵华，田惠玉，杨秀芬，等.气道压力释放通气应用于急性肺损伤/急性呼吸窘迫综合征患者的研究[J].临床肺科杂志，2016，21（5）：802-805.
[4]	李峥，钱素云，王荃，等.呼吸道压力释放通气在儿童重症肺炎并急性呼吸窘迫综合征中的应用[J].中华实用儿科临床杂志，2015，30（17）：1347-1349.
[5]	张坤，周青云，王利军，等.应用肺保护性通气策略进行呼吸支持治疗孕产妇急性呼吸窘迫综合征[J].中国妇幼保健，2014，29（27）：4500-4502.
[6]	黄健，周健，杨文群，等.气道压力释放通气用于创伤后急性呼吸窘迫综合征的效果观察[J].第三军医大学学报，2008，30（12）：1212-1213.
[7]	中华医学会重症医学分会.急性肺损伤/急性呼吸窘迫综合征诊断与治疗指南（2006）[J].中华急诊医学杂志，2007，16（4）：21-22.
[8]	蔡英丽，詹红.呼气末二氧化碳分压联合平台压监测在急性呼吸窘迫综合征机械通气中的应用进展[J].医学综述，2017，23（6）：1210-1214.
[9]	杨海英.压力控制法治疗肺内源性急性呼吸窘迫综合征的疗效及安全性[J].实用临床医药杂志，2014，18（19）：106-107.
[10]	屈昕.肺保护性通气对单肺通气患者肺功能及炎性因子的影响[J].临床肺科杂志，2017，22（2）：364-366.
[11]	吴小静，夏金根.应变导向的急性呼吸窘迫综合征肺保护性通气[J].中日友好医院学报，2015，29（4）：248-250.
[12]	钟华强，黄可赞.肺保护性通气治疗急性呼吸窘迫综合征的疗效观察[J].中国临床新医学，2015，5（9）:187-188.
[13]	刘孝桥，涂睿.经鼻不同正压通气模式在治疗早产新生儿呼吸窘迫综合征的临床比较[J].临床肺科杂志，2017，22（7）：1282-1285.
[14]	喻文亮.急性呼吸窘迫综合征的肺保护性通气治疗现状和再认识[J].中华实用儿科临床杂志，2016，31（18）：1381-1383.
[15]	管双仙，于明，袁冬，等.神经电活动辅助通气模式和压力支持通气模式对急性呼吸窘迫综合征患者肺内气体分布影响的比较[J].临床麻醉学杂志，2016，32（11）：1101-1104.