右美托咪定在体外循环心脏手术中的应用研究进展

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Abstract Dexmedetomidine,a highly selective α2agonist,provides dose-dependent sedation,analgesia,and anti-sympathetic activity.It alleviates the stress associated with anesthesia and surgery,without obvious respiratory depression.Dexmedetomidine as an anesthetic adjunct was widely used in clinical anesthesia.Recently,studies have shown that perioperative administration of dexmedetomidine decreases the need for anesthetics and maintains hemodynamic stability.It induces myocardial protection and anti-inflammatory effects and significantly reduces the incidence of perioperative cardiovascular events in patients undergoing cardiac surgery with cardiopulmonary bypass.Therefore,perioperative dexmedetomidine improves the recovery of the patients undergoing cardiac surgery.This paper mainly elaborate the clinical use of dexmedetomidine in patients undergoing cardiac surgery with cardiopulmonary bypass.

Key words： Dexmedetomidine Cardiopulmonary bypass Cardiac surgery Myocardial protection Anesthesia

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	ZHONG He-jiang
	YANG Tian-de

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ZHONG He-jiang,YANG Tian-de. Research progress of the application of Dexmedetomidine in cardiac surgery with cardiopulmonary bypass[J]. 中国当代医药, 2018, 25(9): 25-28.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I9/25

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