贝那普利、美托洛尔分别给药与联合给药治疗老年原发性高血压并心力衰竭的效果对比

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Abstract Objective To investigate the clinical effects of Benazepril and Metoprolol in the treatment of elderly patients with essential hypertension and heart failure.Methods 90 elderly patients with essential hypertension and heart failure who treated in our hospital from February 2014 to December 2016 were selected as subjects.They were randomly divided into three groups,each group with 30 cases.The patients in the control group 1 were treated with Benazepril,the patients in the control group 2 were treated with Metoprolol,and the patients in the study group were treated with Benazepril combined with Metoprolol.The clinical efficacy,blood pressure,heart rate and indexs of cardiac function of the three groups were compared.Results The total effective rate of clinical treatment in the study group (96.67%)was significantly higher than that in the control group 1 (76.67%)and the control group 2 (73.33%),and the differences were statistically significant(P＜0.05).After intervention,the blood pressure and heart rate of the patients in the study group were lower than that of the control group 1 and the control group 2,and the differences were statistically significant(P＜0.05).After intervention,the levels of LVESD and LVEDD in the study group were significantly lower than those in the control group 1 and the control group 2,the levels of LVEF and 6MWT were higher than those of the control group 1 and the control group 2,and the differences were statistically significant(P＜0.05).Conclusion In the treatment of elderly patients with essential hypertension and heart failure,Benazepril combined with Metoprolol treatment can significantly improve the treatment effect,not only a good pressure control effect can also improve the patients′cardiac function,worthy of clinical use.

Key words： Benazepril Metoprolol Elderly Primary hypertension Heart failure

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	LAI Mu-qiao
	HUANG Fei-xiong
	WU Xiao-feng

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LAI Mu-qiao,HUANG Fei-xiong,WU Xiao-feng. Comparison of the effects of Benazepril and Metoprolol in the treatment of elderly patients with essential hypertension and heart failure[J]. 中国当代医药, 2018, 25(1): 54-56转60.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I1/54

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