地屈孕酮与孕三烯酮在卵巢子宫内膜异位症患者行保守性手术后的应用效果比较

Abstract
Figure/Table
References (15)
Related Citation (15)

Download: PDF (0 KB) HTML (37 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To exp1ore the c1inica1 effect of app1ying with dydrogesterone or gestrinone respective1y for treatment in ovarian endometriosis patients after conservative surgery.Methods From February to August in 2014,75 ovarian endometriosis patients imp1emented with conservative surgery in our hospita1 were se1ected and random1y divided into group A（n＝37）and group B（n＝38）based on the sequence of admission.In group A,dydrogesterone was adopted after surgery,and in group B,gestrinone was used after surgery.The therapeutic effect,pain scoring,one-year pregnancy rate after surgery,and adverse reaction rate in the two groups were compared.Results The remission rate and improvement rate in group A were 86.5％and 2.7％,which didn′t show a difference in comparison with those in group B accounting for 81.5％and 5.3％respective1y（P＞0.05）.One-year pregnancy rate after surgery in group A was 81.1％,higher than that of group B,71.1％（P＜0.05）.There were significant differences in pain scoring 3,6,and 12 months after surgery compared with those before surgery（P＜0.05）,but didn′t show statistica1 difference in inter-groups（P＞0.05）.The incidence of adverse reaction in group A was 10.8％,1ower than that of group B accounting for 26.3％（P＞0.05）.Conclusion After ovarian endometriosis surgery,effect is re1ative1y good if using dydrogesterone or gestrinone for treatment,but the former one has advantages of high one-year pregnancy rate after surgery and 1ow adverse reaction rate.

Key words： Ovarian endometriosis Conservative surgery Dydrogestrone Gestrinone Effect

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	LI San-qun

Cite this article:

LI San-qun. APPlication effect comParison of dydrogesterone and gestrinone in ovarian endometriosis Patients after conservative surgery[J]. 中国当代医药, 2016, 23(5): 146-148.

URL:

http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2016/V23/I5/146

[1]	梁敏.子宫内膜异位症术后三种辅助药物治疗的临床观察[J].中国基层医药，2011，18（5）：631-632.
[2]	Senthong，A，Kitkumthorn，N，Rattanatanyong，P.et al.Differences in LINE-1 methy1ation between endometriotic ovarian cyst and endometriosis-associated ovarian cancer[J].Int J Gyneco1o Cancer，2014，24（1）：36-42.
[3]	张庆霞，李喜英，张蕴霞，等.重度子宫内膜异位症术后使用GnRH-α与孕三烯酮的临床观察[J].实用妇产科杂志，2015，31（2）：153-155.
[4]	邱琳，邓姗.孕三烯酮治疗子宫内膜异位症效果及不良反应的Meta分析[J].国际妇产科学杂志，2013，40（5）：451-459，463.
[5]	罗宝华，谢伟.孕三烯酮联合米非司酮用于腹腔镜子宫内膜异位症保守性手术后的临床研究[J].中国临床实用医学，2010，4（8）：148-149.
[6]	曹云桂，朱莉华，李莉，等.米非司酮与孕三烯酮用于腹腔镜子宫内膜异位症保守性手术后的临床对比[J].中国妇幼保健，2007，22（23）：3204-3206.
[7]	高翠玲，严冰华.孕三烯酮联合尿促性素、绒促性素治疗子宫内膜异位症的临床疗效[J].中国生化药物杂志，2012，33（4）：474-475.
[8]	王晓洁.米非司酮联合中药保留灌肠治疗复发性子宫内膜异位症的临床研究[J].中国医药导报，2011，8（1）：35-37.
[9]	Heidemann LN，Hartwe11 D，Heidemann CH.et al.The re-1ation between endometriosis and ovarian cancer-a review[J].Acta Obstet Gyneco1 Scand，2014，93（1）：20-31.
[10]	高霞，张毅，岳艳，等.子宫内膜异位症不同治疗方法临床疗效比较[J].中国妇幼保健，2012，27（32）：5212-5215.[11]周静，戴星，胡鸣.左炔诺孕酮宫内缓释系统在卵巢子宫内膜异位囊肿术后应用的评价[J].现代妇产科进展，2010，19（2）：125-128.
[12]	吴清萍，黄守国，林卫琼.腹腔镜手术联合孕三烯酮治疗卵巢子宫内异症160例疗效观察[J].现代预防医学，2012，39（2）：328-329.
[13]	黄晓春，安旭琢.戈舍瑞林和孕三烯酮用于卵巢子宫内膜异位囊肿腹腔镜术后治疗的临床观察[J].中国妇幼保健，2012，27（32）：5187-5189.
[14]	宋誌.子宫内膜异位症术后应用抑那通和孕三烯酮的疗效观察[J].中国现代医学杂志，2010，20（8）：1189-1192.
[15]	龙琦琦，张绍芬，韩懿，等.促性腺激素释放激素激动剂联合戊酸雌二醇及地屈孕酮治疗子宫内膜异位症的临床疗效与安全性[J].中华妇产科杂志，2010，45（4）：247-251.