|
|
|
| Clinical effect of Bifidobacterium triPle viable Powder combined with mesalazine enteric coated tablets in the treatment of Patients with ulceratire colitis |
| GAO Lei1 XUE Juan2 |
1.Department of Digestive,the First Affi1iated Hospita1 of Henan University of Science and Techno1ogy,Luoyang 471000,China;
2.Department of Laboratory,the First Affi1iated Hospita1 of Henan University of Science and Techno1ogy, Luoyang 471000,China |
|
|
|
|
Abstract Objective To observe the effect of Bifidobacterium trip1e 1ive bacteria powder scattered us joint mesa1azine enteric coated tab1ets in the treatment of the c1inica1 efficacy of patients with u1cerative co1itis.Methods 80 cases of patients with u1cerative co1itis from June 2014 to June 2015 were divided into two groups based on the random number tab1e,40 cases in each group.The contro1 group were treated with mesa1azin enteric-coated tab1ets,observation group were treated with Bifidobacterium trip1e viab1e powder combined with mesa1azin enteric-coated tab1ets treatment.The treatment effects and adverse reactions of the two groups were observed.Results The treatment tota1 effective rate of observation group was 90.0％,significant1y higher than that of contro1 group 75.0％,there was statistica1 significance（P＜0.05）.After treatment,superoxide dismutase（SOD）,ma1ondia1dehyde（MDA）,IL-6,IL-8,IL-10,tumor necrosis factor-α （TNF-α）and u1tra sensitivity C-reactive protein（hs-CRP）expression 1eve1 in the observation group were significant1y improved compared with the contro1 group,there was statistica1 significance（P＜0.05）.Conclusion Bifidobacterium trip1e 1ive bacteria powder scattered us joint mesa1azine enteric coated tab1ets are effective in the treatment of u1cerative co1itis patients can improve cytokines expression.
|
|
|
|
|
|
| [1] |
李匡一，张亚历，崔西玉，等.溃疡性结肠炎治疗后黏膜愈合程度与预后的关系的研究[J].中华消化内镜杂志，2014，31（2）：80-83.
|
| [2] |
于燕林.溃疡性结肠炎患者血清TNF-α和IL-10的临床观察[J].中国当代医药，2010，17（24）：79-80.
|
| [3] |
孙达龙，陈凤媛，潘勤聪.溃疡性结肠炎的药物治疗现状及进展[J].中华全科医师杂志，2014，13（11）：916-919.
|
| [4] |
刘召茹，周茂京.美沙拉嗪联合川芎嗪治疗溃疡性结肠炎的临床疗效[J].中国当代医药，2011，18（29）：86-87.
|
| [5] |
张怡.环磷酰胺治疗老年中重型溃疡性结肠炎45例的疗效观察[J].中国老年学杂志，2010，30（15）：2220-2221.
|
| [6] |
顾于蓓，袁耀宗.上海地区老年溃疡性结肠炎患者临床特点的初步探讨[J].中华消化杂志，2011，31（3）：155-159.
|
| [7] |
李琨，张彩凤，夏永华，等.微生态制剂对溃疡性结肠炎的治疗效果及作用机制研究[J].中华胃肠外科杂志，2013，16（4）：336-339.
|
| [8] |
潘伟明.活动期溃疡性结肠炎血清C反应蛋白及CA125检测的价值探讨[J].中国当代医药，2011，18（5）：70-71.
|
| [9] |
李勇，谢宜奎，丁红玲，等.美沙拉嗪与康复新液联合治疗溃疡性结肠炎的临床疗效及患者血清细胞因子的变化[J].山东医药，2012，52（25）：55-56.
|
| [10] |
樊慧丽，陈玉梅.溃疡性结肠炎的发病机制和治疗进展[J].中国全科医学，2012，15（2）：228-230.
|
| [11] |
雷晓燕，崔梅花.溃疡性结肠炎的治疗进展[J].山东医药，2014，54（6）：99-102.
|
| [12] |
于海食，洪缨，王玉蓉，等.溃疡性结肠炎发病机制[J].实用医学杂志，2010，26（2）：323-325.
|
| [13] |
陈爱民，刘永芬，熊雯雯，等.芪仙汤对溃疡性结肠炎患者血清TNF-α，IL-8的影响及疗效观察[J].中国实验方剂学杂志，2011，17（8）：255-257.
|
| [14] |
张娟，曹泽伟.清肠愈疡汤联合美沙拉嗪治疗溃疡性结肠炎的疗效分析[J].中国全科医学，2012，15（1）：90-92.
|
| [15] |
王君丽.微生态制剂对溃疡性结肠炎患者治疗前后临床疗效分析[J].中国医药导刊，2011，13（9）：1540-1541.
|
|
|
|
