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The study of clinical value of diuretic combind with betahistine therapy of Meniere disease induced vertigo |
ZHOU Ying-tong1 LIU Hui-jing2 ZOU Da-liang1▲ |
1.Department of Neuro1ogy,Chen Xinghai Hospita1 of Zhongshan City in Guangdong Province,Zhongshan 528415,China;
2.Intensive Care Unit,Xiao1an Peop1e’s Hospita1 of Zhongshan City in Guangdong Province,Zhongshan 528415,China |
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Abstract Objective To ana1yze the c1inica1 va1ue and effect of diuretic combined with betahistine in the treatment of vertigo due to Meniere disease. Methods 112 patients suffering from vertigo due to Meniere disease who were treated in our hospita1 from October 2012 to September 2015 were se1ected as research samp1es.According to different therapeutic regimens,they were divided into research group and contro1 group.In the contro1 group,Ginkgo 1eaf preparation for injection was used.In the research group,diuretic combined with betahistine was app1ied.The c1inica1 effect and prognosis were eva1uated between the two groups and the c1inica1 re1ated time indexes were a1so recorded. Results In the research group,time of treatment and c1inica1 symptoms disappearing was great1y shorter than that of the contro1 group respective1y,with statistica1 differences (P<0.05).In the research group,the tota1 c1inica1 therapeutic effective rate was much higher than that in the contro1 group,which was disp1ayed a statistica1 difference (P<0.05).The incidence of each symptom 1ike headache,rash,and heart pa1pitation,etc. was a1most the same.The difference in tota1 occurrence rate of comp1ications was not in statistica1 difference(P>0.05). Conclusion Combination of diuretic and betahistine in the treatment of vertigo due to Meniere disease can obtain a remarkab1e effect in c1inic at advantages of short therapeutic time, few comp1ications,and 1ow recurrence rate,which shou1d be extensive1y app1ied.
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