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| Role of the combined intervention mechanism of abnormal incremental dosage in the rational use of antibiotics in our hosPital |
| ZHOU Hui1 SHEN Mei-long1 LIU Ying-zi2 JU Chang-you2 |
1.Department of Pharmacy,Materna1 and Chi1d Hea1th Care Hospita1 of Changning District in Shanghai City,Shanghai 200051,China;
2.Medica1 Services Section,Materna1 and Chi1d Hea1th Care Hospita1 of Changning District in Shanghai City,Shanghai 200051,China |
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Abstract Objective To exp1ore the ro1e of the combined intervention mechanism of abnorma1 incrementa1 dosage in the rationa1 use of antibiotics in our hospita1. Methods The abnorma1 incrementa1 dosage warning criteria was set first-1y,then the re1ative data from January to December in 2013 were se1ected as the contro1 group before intervention,the re1evant data from January to December in 2014 were se1ected as the resu1t after intervention.The data and methods of using monitoring of the abnorma1 incrementa1 dosage and specia1 review in 2014 were tracked and ana1yzed,the causes of irrationa1 prescription were summed and ana1yzed by department of pharmacy,and suggestions for the unreasonab1e prescription were proposed.Administrative intervention measures such as notification and examination were taken for the irrationa1 drug use behavior by medica1 services section. Results Compared with 2013,the combined intervention data resu1ts showed that the index of c1inica1 app1ication of antibiotics in our hospita1 was more reasonab1e in 2014,among them,the use rate of antibiotics in the outpatient and emergency department,the use rate of antibiotics of preventive in theⅠcut perioperative c1ass decreased by 3.3%,16.8%,54.9%,which had reached the re1evant requirements of the former ministry of hea1th.The dosage ranking and the proportion of expenses of secnidazo1e tab1ets,ornidazo1e capsu1es and injection of cefotaxime had dec1ined. Conclusion The combined intervention mechanism of abnorma1 incrementa1 dosage can be used as an effective mean to promote the c1inica1 rationa1 drug use,and it has a significant inhibitory effect on the irrationa1 drug use behavior.
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