[1] |
Ravikumar B,Sarkar S,Davies JE,et al.Regulation of mammalianautophagyinphysiologyandpathophysiology[J].Physiol Rev,2010,90(4):1383-1435.
|
[2] |
Klionsky DJ,Codogno P,Cuervo AM,et al.A comprehensive glossary of autophagy-related molecules and processes[J].Autophagy,2010,6(4):438-448.
|
[3] |
Simonsen A,Tooze SA.Coordination of membrane events during autophagy by multiple classⅢPI3-kinase complexes[J].J Cell Biol,2009,186(6):773-782.
|
[4] |
Chang YY,Neufeld TP.An Atg1/Atg13 complex with multiple roles in TOR-mediated autophagy regulation[J].Mol Biol Cell,2009,20(7):2004-2014.
|
[5] |
Jung CH,Ro SH,Cao J,et al.mTOR regulation of autophagy[J].FEBS Lett,2010,584(7):1287-1295.
|
[6] |
Benjamin D,Colombi M,Moroni C,et al.Rapamycin passes the torch:a new generation of mTOR inhibitors[J].Nat Rev Drug Discov,2011,10(11):868-880.
|
[12] |
杨湘怡,陶润知,聂亚雄.mTOR依赖的自噬通路与神经变性疾病[J].中南医学科学杂志,2014,40(2):191-195,214.
|
[20] |
Jin Y,Wang H,Cui X,et al.Role of autophagy in myocardial reperfusion injury[J].Front Biosci(Elite Ed),2010,2:1147-1153.
|
[7] |
Maiese K,Chong ZZ,Shang YC,et al.mTOR:on target for novel therapeutic strategies in the nervous system[J].Trends Mol Med,2013,19(1):51-60.
|
[8] |
Zeng Z,Sarbassov DD,Samudio IJ,et al.Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML[J].Blood,2007,109(8):3509-3512.
|
[9] |
Cleary JM,Shapiro GI.Development of phosphoinositide-3 kinase pathway inhibitors for advanced cancer[J].Curr Oncol Rep,2010,12(2):87-94.
|
[10] |
Don AS,Tsang CK,Kazdoba TM,et al.Targeting mTOR as a novel therapeutic strategy for traumatic CNS injuries[J]. Drug Discov Today,2012,17(15-16):861-868.
|
[11] |
Meley D,Bauvy C,Houben-Weerts JH,et al.AMP-activated protein kinase and the regulation of autophagic proteolysis[J].J Biol Chem,2006,281(46):34870-34879.
|
[13] |
Criollo A,Senovilla L,Authier H,et al.The IKK complex contributes to the induction of autophagy[J].EMBO J,2010,29(3):619-631.
|
[14] |
Chen Y,Gibson SB.Is mitochondrial generation of reactive oxygen species a trigger for autophagy?[J].Autophagy,2008,4(2):246-248.
|
[15] |
Gao C,Cai Y,Zhang X,et al.Ischemic preconditioning mediates neuroprotection against ischemia in mouse hippocampal CA1 neurons by inducing autophagy[J].PLoS One,2015,10(9):e0137146.
|
[16] |
Gao L,Jiang T,Guo J,et al.Inhibition of autophagy contributes to ischemic postconditioning-induced neuroprotection against focal cerebral ischemia in rats[J].PLoS One,2012,7(9):e46092.
|
[17] |
Zeng M,Wei X,Wu Z,et al.Reactive oxygen species contribute to simulated ischemia/reperfusion -induced autophagic cell death in human umbilical vein endothelial cells[J].Med Sci Monit,2014,20:1017-1023.
|
[18] |
Wang ZG,Wang Y,Huang Y,et al.bFGF regulates autophagy and ubiquitinated protein accumulation induced by myocardial ischemia/reperfusion via the activation of the PI3K/Akt/mTOR pathway[J].Sci Rep,2015,5:9287.
|
[19] |
Matsui Y,Takagi H,Qu X,et al.Distinct roles of autophagy in the heart during ischemia and reperfusion:roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy[J].Circ Res,2007,100(6):914-922.
|
[21] |
Hariharan N,Zhai P,Sadoshima J.Oxidative stress stimulates autophagic flux during ischemia/reperfusion[J].Antioxid Redox Signal,2011,14(11):2179-2190.
|
[22] |
Gedik N,Thielmann M,Kottenberg E,et al.No evidence for activated autophagy in left ventricular myocardium at early reperfusion with protection by remote ischemic preconditioning in patients undergoing coronary artery bypass grafting[J].PLoS One,2014,9(5):e96567.
|
[23] |
Chien CT,Shyue SK,Lai MK.Bcl-xL augmentation potentially reduces ischemia/reperfusion induced proximal and distal tubular apoptosis and autophagy[J].Transplantation,2007,84(9):1183-1190.
|
[24] |
Jiang M,Liu K,Luo J,et al.Autophagy is a renoprotective mechanism during in vitro hypoxia and in vivo ischemiareperfusion injury[J].Am J Pathol,2010,176(3):1181-1192.
|
[25] |
Suzuki C,Isaka Y,Takabatake Y,et al.Participation of autophagy in renal ischemia/reperfusion injury[J].Biochem Biophys Res Commun,2008,368(1):100-106.
|