112例LEEP环切病理诊断与宫颈液基细胞学及活检结果对比分析

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Abstract Objective To explore the difference of pathology diagnose results among loop electrosurgical excision procedure（LEEP），liquid-based cytology test（LCT）and multi-point biopsy under colposcope.Methods 112 patients with cervix LEEP treatment were selected as study object.The difference of pathology diagnose results among LEEP，LCT and multi-point biopsy under colposcope were analyzed.Results The coincidence rate between LCT and LEEP was 72.32% （81/112）；The coincidence rate between multi-point biopsy under colposcope and LEEP pathology diagnose was 75.89%（85/112）.Compared the results among LEEP，LCT and multi-point biopsy under colposcope，the difference had obvious difference（P＜0.05）.2 cases of LCT showed that cervical high-grade squamous intraepithelial neoplasia and the biopsy result was negative，but pathology diagnose result of LEEP was CINⅡ.Conclusion The LCT cytological examination，the pathology results of multi-point biopsy under colposcope and LEEP have difference，CIN diagnosis of only relying on cytology result by clinicians are not sufficient；CIN has the feature of multifocal coexistence，microscopically multi-point biopsy has limits.When liquid-based cytology test is abnormal but biopsy is normal，cervical loop resection is appropriate.

Key words： Loop electrosurgical excision procedure Cervical intraepithelial neoplasia Liquid-based cytology test Multi-point biopsy

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	LI You-heng
	XU Hong
	ZENG Xun

Cite this article:

LI You-heng,XU Hong,ZENG Xun. ComParing analysis of LEEP Pathology diagnose and liquid-based cytology and bioPsy result of cervix[J]. 中国当代医药, 2016, 23(15): 112-114.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2016/V23/I15/112

［1］	张文花.81例宫颈癌临床病例分析［J］.中国计划生育学杂志，2015，23（7）：491-493.
［2］	乔友林，章文华，李凌，等.子宫颈癌筛查方法的横断面比较研究［J］.中国医学科学院学报，2002，24（1）：50-53.
［3］	李园园，王英红.人乳头状瘤病毒与宫颈癌及其癌前病变的研究进展［J］.中国医师杂志，2012，14（9）：1290-1292.
［4］	殷霞，狄文.早期宫颈癌治疗新进展［J］.中国妇幼保健，2005，20（20）：2735-2737.
［5］	郎景和.子宫颈癌预防的现代策略［J］.中国医学科学院学报，2007，29（5）：575-578.
［6］	甘密密，张锡流.DNA定量分析及LCT技术诊断宫颈病变的临床研究［J］.实用妇产科杂志，2014，30（9）：674-677.
［7］	连利娟.林巧稚妇科肿瘤学［M］.4版.北京：人民卫生出版社，2006：105-107.
［8］	Frable WJ，Austin RM，Collins RJ，et al.Medicolegal affairs：IAC task force summary［J］.Acra Cytol，1988，42（1）：76-119.
［9］	Bello BD，Spinillo A，Alberizzi P，et al.Cervical infections by multiple human papillomavirus（HPV）genotypes：prevalenc and impact on the risk of precancerous epithelial lesion［J］.Med Virol，2009，81（4）：703-712.
［10］	唐学研，杨秀群.宫颈癌筛查的意义及进展［J］.实用医学杂志，2009，25（5）：687-688.
［11］	杨怡卓，李亚里，徐滨，等.LCT在宫颈病变筛查中的临床价值及不足［J］.中国妇产科临床杂志，2008，9（2）：87-89.
［12］	Lurie S，Eliaz M，Boaz M，et al.Distribution of cervical intraepithelial neoplasia across the cervix is random［J］. Am J Obstet Gynecol，2007，196（2）：125.
［13］	张金瑾.宫颈锥形切除对阴道镜下多点活检诊断宫颈上皮内瘤样病变及早期宫颈癌的再评价［J］.安徽医药，2014，18（5）：895-896.
［14］	沈铿，郎景和，黄惠芳，等.子宫颈锥切术在子宫颈上皮内瘤变诊断和治疗中的价值［J］.中华妇产科杂志，2001，36（5）：264-266.
［15］	Nagai N，Mukai K，Oshita T，et al.Human papillomavirus DNA status after loop excision for cervical intraepithelial neoplasia gradeⅢ-A prospective study［J］.Int J Mol Med，2004，13（4）：589-593.
［16］	Cho H，Kim JH.Treatment of the patients with abnormal cervical cytology：a"see-and-treat"versus three-step strategy［J］.J Gynecol Oncol，2009，20（3）：164-168.
［17］	Kietpeerakool C，Srisomboon J，Khobjai A，et al.Complicationsofloopelectrosurgicalexcisionprocedureforcervical neoplasia：a prospective study［J］.J Med Assoc Thai，2006，89（5）：583-587.