可溶性髓系细胞触发受体-1在骨科感染患者中的表达及其意义

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Abstract Ob jective To explore the serum concentration change of serum soluble triggering receptor expressed on myeloid cells-1（sTREM-1）from the orthopaedic infection patients and to find a new objective index for clinical diagnosis.M ethods 30 patientswith orthopaedic infection from April 2015 to March 2016 in our hospital were selected as the infection group，30 healthy people were selected as the control group.The fasting venous blood was collected in the earlymorning of all the cases.The serum concentration of sTREM-1 was determined by ELSIA method，and the results were statistically analyzed.Resu lts The average concentration of sTREM-1 in the infection group was higher than that in the control group，with significant difference（P＜0.05）.The positive rate of infection group was 93.3%，which was higher than 10.0%in the control group，with significant difference（P＜0.05）.Conclusions sTREM-1 is a valuable predictor for the early diagnosis of blood stream orthopaedic infection.The rising of the serum concentration of sTREM-1 suggests the presence of infection，excluded other infections，which provides strong evidence to guide the reasonable use of antibiotics.

Key words： Soluble triggering receptor expressed on myeloid cells-1 Orthopaedic infection Antibiotics

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	Articles by authors
	GUO Yong-xian
	SONG Shi-jiang
	ZHOU Xian-wei
	FANG Zhong-wei
	CHEN Yun-hao
	LIN Xue-lin

Cite this article:

GUO Yong-xian,SONG Shi-jiang,ZHOU Xian-wei, et al. Expresses and significance of serum soluble triggering receptor expressed on m yeloid cells-1 in patientsw ith infaction of orthopaedics[J]. 中国当代医药, 2016, 23(21): 23-25.

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