D-二聚体和高敏C反应蛋白对B型主动脉夹层的诊断价值

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Abstract Objective To investigate the diagnostic value of D-dimer and high-sensitivity C-reactive protein for type B aortic dissection. Methods 42 patients with type B aortic dissection treated by our hospital from June 2013 to June 2015 were selected and they were divided into typical and atypical type B aortic dissection　（intramural hematoma and penetrating atherosclerotic ulcer）according to the admission examination results.D-dimer and C-reactive protein level in patients were detected respectively 12 h，24 h，72 h and two weeks after disease onset.Relationship between different type B aortic dissection and the above-mentioned two indicatorswas analyzed.Results After incidence of aortic dissection，D-dimer and C-reactive protein level in patients increased to varying degree.D-dimer of typical and atypical type B aortic dissection was　（875.0±190.0）ng/ml，（1021.0±386.0）ng/ml，（2056.0±912.0）ng/ml，（6780.0±1163.0）ng/ml and （926.0±108.0）ng/ml，（989.0±320.0）ng/ml，（1478.0±825.0）ng/ml，（3568.0±1558.0）ng/ml respectively 12 h，24 h，72 h and two weeks after disease onset.C-reactive protein typical and atypical type B aortic dissection was　（25.8±11.4）mg/L，（60.9±9.7）mg/L，（110.0±27.5）mg/L，（86.4±21.8）mg/L and（29.1±14.5）mg/L，（44.7±11.2）mg/L，（103.2±25.4）mg/L，（79.5± 36.3）mg/L respectively 12 h，24 h，72 h and two weeks after disease onset.D-dimer level in patients with typical type B aortic dissection was obviously higher than that of patientswith atypical type B aortic dissection（P＜0.05）.There was no statistical difference of high-sensitivity C-reactive protein between two groups　（P＞0.05）.Conclusion D-dimer and high-sensitivity C-reactive protein are helpful in the diagnosis of aortic dissection，and D-dimer contribute to the differential diagnosis of type B aortic dissection.

Key words： Aortic dissection D-dimer C-reactive protein

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