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| Clinical effect of Ebastine in the treatment of allergic rhinitis |
| HE Zhi-qiang CHEN Juan |
| Department of Otorhinolaryngology,Provincial Clinical Medicine College of Fujian Medical University,Fuzhou 350001, China |
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Abstract ObjectiveTo explore the clinical effect of Ebastine in the treatment of allergic rhinitis (AR).Methods110 patients with AR from November 2013 to April 2015 in our hospital were selected and randomly divided into the control group and the study group,55 cases in each group.The study group was treated with orally Ebastine,the control group was treated with orally Loratadine.The total effective rate,the incidence rate of adverse reactions and the level of serum adhesion molecule-1(VCAM-1),interleukin-10(IL-10),interleukin-4(IL-4)in the two groups were compared.ResultsThe total effective rate of the study group was 94.55%,which was higher than 80.00%of the control group,with significant difference (P＜0.05).There was no significant difference in the incidence rate of adverse reactions between the two groups(P＞0.05).The level of serum VCAM-1,IL-10 and IL-4 after treatment in the study group was lower than that in the control group after treatment,with significant difference (P＜0.05).ConclusionThe effect of Ebastine in the treatment of AR is significant,which can significantly improve the inflammatory reaction and related symptoms in patients with AR,it is worthy of popularization and application.
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