不同类型高血压病患者血浆BNP浓度的临床意义

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Abstract Objective To explore the clinical significance of plasma BNP concentration in different types of hypertension patients.Methods 180 patients with essential hypertension were selected from July 2014 to July 2015，and were respectively divided into pure systolic hypertension group(n=60),pure diastolic hypertension group(n=60)and double hypertension group(sutra hypertension group)(n=60).Then according to cardiac color ultrasound were divided into with, without left atrial enlargement and left ventricular hypertrophy in two subgroups.All of the subjects were monitored in plasma BNP concentration,liver function,renal function,blood lipid indexes,the collected data were analyzed statistically and got the results.Results Plasma concentration of BNP in double hypertension group was higher than that of pure systolic hypertension group and pure diastolic hypertension group(P＜0.01).The concentration of BNP of three groups patients with hypertension and atrial ventricular enlargement was higher than that of normal atrial ventricular(P＜0.01). The concentration of BNP and atrial and ventricular enlargement,renal function,systolic pressure,diastolic positive correlation were existed between pressure (P＜0.01).Conclusion Plasma BNP concentration is the objective evaluation of primary hypertension patients in blood pressure level and a sensitive index of left atrial enlargement and left ventricular enlargement.Monitoring the plasma concentration of BNP may become an important index to judge the severity of hypertension and provide the basis for the diagnosis and treatment of hypertension.

Key words： Isolated diastolic hypertension Isolated systolic hypertension Systolic and diastolic hypertension Brain natriuretic peptide Systolic blood pressure Diastolic blood pressure

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	YANG Jing-yu
	LIU Dan

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YANG Jing-yu,LIU Dan. The clinical significance of the different types of high blood pressure patients plasma BNP concentration[J]. 中国当代医药, 2017, 24(4): 42-44.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I4/42

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