舒利迭联合无创通气救治老年COPD伴呼吸衰竭的临床研究

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Abstract Objective To study the clinical effects of Seretide combined with noninvasive ventilation in treating chronic obstructive pulmonary disease (COPD)with respiratory failure in the elderly.Methods 40 elderly COPD patients with respiratory failure in our hospital from January 2014 to November 2015 were selected and divided into observation group and control group according to random draw,and each group was 20 cases.Patients in the control group were given noninvasive ventilation,and patients in the observation group were given Seretide combined with noninvasive ventilation.The respiratory rate(RR),heart rate(HR)and change level of peak expiratory flow rate(PEF)in two groups were compared.Before and after treatment,the blood gas indexes liked partial pressure of blood oxygen (PaO2),arterial carbon dioxide partial pressure (PaCO2),hydrogen ion concentration index (pH),the change of lung function index liked forced expiratory volume in one second(FEV1),forced vital capacity(FVC)in two groups were compared.Results After treatment,RR and HR in the observation group was obvious lower than that in the control group(P＜0.05).After treatment,the level of PaO2,pH in the observation group obvious increased than that in the control group (P＜0.05);the level of PaCO2in the observation group was decreased obviously than that in the control group (P＜0.05).After treatment,the level of FEV1/FVC in the observation group was increased obviously than that in the control group (P＜0.05).Conclusion Seretide combined with noninvasive ventilation in treating COPD with respiratory failure in the elderly with obvious effects, which can make the patient′s breathing,heart rate gradually return to normal,improve arterial blood gas levels effectively and enhance the lung function.This method is worth to popularize in clinic.

Key words： Seretide Noninvasive ventilation Chronic obstructive pulmonary disease Respiratory failure

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	LIU Sen-guan
	LIU Kai
	TAN Bai-he
	YU Yu-hao

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LIU Sen-guan,LIU Kai,TAN Bai-he, et al. Clinical study of Seretide combined with noninvasive ventilation in treating chronic obstructive pulmonary disease with respiratory failure in the elderly[J]. 中国当代医药, 2017, 24(4): 26-28.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I4/26

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