精神疾病住院患者合并细菌感染的菌种分布及药敏分析

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Abstract Objective To understand the characteristics of bacterial infection in hospitalized patients with mental disorders,and to provide references for rational use of antibiotics and prevention of nosocomial infection.Methods The results of bacterial culture were analyzed retrospectively of various types of inspection specimens of inpatients with mental disease complicated with bacterial infection of the Fifth People′s Hospital of Nanning City from July 2013 to June 2016.Statistics released by the WHO for drug resistance analysis software version WHONET 5.6,the detection rate of pathogenic bacteria,the composition of pathogens,the distribution and drug resistance of the strains,and the age distribution of the infected people were statistically analyzed.Results Among 2382 clinical specimens,the sputum,throat swabs,blood,urine samples were the mainl types.The conventional sterile specimen accounted for 30.6%.A total of 349 strains of bacteria were isolated,the total positive rate was 14.7%,and the positive rate was the highest in the secretions and urine samples.There were 222 strains(63.6%)from respiratory specimens,and 62 (17.8%)samples were obtained from urinary tract specimens.The pathogens were Klebsiella pneumoniae,Staphylococcus aureus,Mlicrococcus scarlatinae, Escherichia coli,Streptococcus pneumoniae,Pseudomonas aeruginosa in the top 6.Staphylococcus aureus detection rate of MRSA was 20.05%,there was a rising trend,no Vancomycin,Linezolid resistant strains.The resistance rate of Streptococcus pyogenes to Erythromycin was 74.5%,Penicillin resistance was not found.Klebsiella pneumoniae producing ESBLs accounted for 6.3%,Escherichia coli producing ESBLs accounted for 21.2%.Patients with pathogenic bacteria,patients whoagedmorethan59yearsaccounted for 57.9%.Conclusion The hospital psychiatric inpatients complicated with bacterial infection pathogenic bacteria distribution and drug sensitivity results has its own characteristics:the infection of respiratory tract infection and urinary tract in elderly patients with mental disease complicated with bacterial infection more,fewer cases of multi drug resistant bacteria infection,but has gradually rising trend.

Key words： Mental illness Inpatients Pathogenic bacteria Bacterial drug resistance

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	LU Xi-jian
	LU Shen-yan
	LU Dan-yu

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LU Xi-jian,LU Shen-yan,LU Dan-yu. Distribution and drug sensitivity analysis of bacterial infection in hospitalized patients with mental disorders[J]. 中国当代医药, 2017, 24(9): 131-134转140.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I9/131

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