降钙素原指导ICU危重患者抗菌治疗的临床价值

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Abstract Objective To investigate the guidance value of procalcitonin (PCT)in the detection of antibacterial agents usage for critically ill infected patients in ICU.Methods 88 cases of critically ill patients in ICU admitted to our hospital from January to December 2016 were selected as study object and divided into routine group and PCT group according to the order of admission with 44 patients respectively in each group,patients in the routine group were treated with antibiotics,and patients in the PCT group were treated with antibiotic by the guidance of PCT content.Each index level before and after treatment,treatment and prognosis in two groups were observed.Results There was no difference in the levels of WBC,CRP and PCT before treatment between two groups(P＞0.05);after treatment,there was still no difference in WBC,CRP and PCT levels between two groups(P＞0.05).The antibiotic use time,ICU hospitalization time and costs of the PCT group was less than that of the routine group(P<0.05).The survival rate and mortality rate of the PCT group was 95.45%and 4.55%respectively,which was significantly higher than 86.36%and 13.64%in the routine group (P＜0.05).Conclusion PCT can play a good role in guiding the treatment of ICU infection in critically ill patients,can significantly reduce the amount of the antibiotics and time,improve the survival rate,which is worthy of clinical promotion and application.

Key words： Procalcitonin ICU Antibacterial therapy

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	ZHENG Wei
	LU Wen

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ZHENG Wei,LU Wen. The clinical value of procalcitonin monitoring antibacterial therapy for critically ill patients in ICU[J]. 中国当代医药, 2017, 24(9): 37-39.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I9/37

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