补钙对骨质疏松骨折预防作用的研究进展

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Abstract Calcium and Vitamin D have widely been recommended for older individuals as a basic therapy to prevent osteoporosis and subsequent fractures,but the effect is not very ideal and research conclusion is a lack of consistency. Some studies support the preventive effect of calcium intake for osteoporosis and fractures,but others may not.And it is not yet clear which benefits more,Calcium with or without vitamin D,from dietary or supplementations,with low or high dose.This review analyzes the high grade evidence,such as cohort studies,randomized controlled studies and Meta analysis from recently published literature,to analyse the efficacy of calcium intake,and present some suggestion for the public to make suitable calcium regime.

Key words： Osteoporosis Fracture Calcium Vitamin D Prevention

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	Articles by authors
	GAO Chun-lin
	JIANG Hong
	TANG Jia-guang
	HOU Shu-xun

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GAO Chun-lin,JIANG Hong,TANG Jia-guang, et al. The research progress of preventive efficacy of calcium intake for osteoporotic fracture[J]. 中国当代医药, 2017, 24(9): 15-17.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I9/15

[1]	中华医学会骨质疏松和骨矿盐疾病分会.原发性骨质疏松诊治指南（2011年）[J].中华骨质疏松和骨矿盐疾病杂志，2011，4（1）：2-15.
[2]	Cosman F，de Beur SJ，LeBoff MS，et al.Clinician′s guide to prevention and treatment of osteoporosis[J].Osteoporos Int，2014，25（10）：2359-2381.
[3]	National Osteoporosis Guideline Group.Diagnosis and management of osteoporosis in postmenopausal women and older men in the UK，update 2013[J].Maturitas，2013，75（4）：392-396.
[4]	Chapuy MC，Arlot ME，Delmas PD，et al.Effect of calcium and cholecalciferol treatment for three years on hip fractures in elderly women[J].BMJ，1994，308（6936）：1081-1082.
[5]	Tang BMP，Eslick GD，Nowson C，et al.Use of calcium or calcium in combination with vitamin D supplementation to prevent fractures and bone loss in people aged 50 years and older：a meta-analysis[J].Lancet，2007，370（9588）：657-666.
[6]	Chung M，Lee J，Terasawa T，et al.Vitamin D with or without calcium supplementation for prevention of cancer and fractures：an updated meta-analysis for the U.S.Preventive Services Task Force[J].Ann Intern Med，2011，155（12）：827-838.
[7]	Whitton C，Nicholson SJ，Roberts C，et al.National Diet and Nutrition Survey：UK food consumption and nutrient intakes from the first year of the rolling programme and comparisons with previous surveys[J].Br J Nutr，2011，106（12）：1899-1914.
[8]	Chapuy MC，Pamphile R，Paris E，et al.Combined calcium and vitamin D3 supplementation in elderly women：confirmation of reversal of secondary hyperparathyroidism and hip fracture risk：the DecalyosⅡstudy[J].Osteoporos Int，2002，13（3）：257-264.
[9]	Peacock M，Liu G，Carey M，et al.Effect of calcium or 25OH vitamin D3 dietary supplementation on bone loss at the hip in men and women over the age of 60[J].J Clin Endocrinol Metab，2000，85（9）：3011-3019.
[10]	Avenell A，Grant AM，McGee M，et al.The effects of an open design on trial participant recruitment，compliance and retention—a randomized controlled trial comparison with a blinded，placebo-controlled design[J].Clin Trials，2004，1（6）：490-498.
[11]	Harwood RH，Sahota O，Gaynor K，et al.A randomised，controlled comparison of different calcium and vitamin D supplementation regimens in elderly women after hip fracture：the Nottingham neck of femur（NONOF）study[J].Age Ageing，2004，33（1）：45-51.
[14]	Tai V，Leung W，Grey A，et al.Calcium intake and bone mineral density：systematic review and meta-analysis[J]. BMJ，2015，351：h4183.
[18]	Bolland MJ，Leung W，Tai V，et al.Calcium intake and risk of fracture：systematic review[J].BMJ，2015，351：h4580.
[20]	Iwamoto J.A role of exercise and sports in the prevention of osteoporosis[J].Clin Calcium，2017，27（1）：17-23.
[12]	Jackson RD，LaCroix AZ，Grass M，et al.Women′s Health Initiative Investigators.Calcium plus vitamin D supplementation and the risk of fractures[J].N Engl J Med，2006，354 （7）：669-683.
[13]	Prince RL，Devine A，Dhaliwal SS，et al.Effects of calcium supplementation on clinical fracture and bone structure：results of a 5-year，double-blind，placebo-controlled trial in elderly women[J].Arch Intern Med，2006，166（8）：869-875.
[15]	Reid IR，Ames R，Mason B，et al.Randomized controlled trial of calcium supplementation in healthy，nonosteoporotic，older men[J].Arch Intern Med，2008，168（20）：2276-2782.
[16]	Bonjour JP，Brandolini-Bunlon M，Boirie Y，et al.Inhibition of bone turnover by milk intake in postmenopausal women[J]. Br J Nutr，2008，100（4）：866-874.
[17]	Salovaara K，Tuppurainen M，Karkkainen M，et al.Effect of vitamin D3and calcium on fracture risk in 65-to 71-yearold women：a population-based 3-year randomized，controlled trial-the OSTPRE-FPS[J].J Bone Miner Res，2010，25（7）：1487-1495.
[19]	Weaver CM，Alexander DD，Boushey CJ，et al.Calcium plus vitamin D supplementation and risk of fractures：an updated meta-analysis from the National Osteoporosis Foundation[J].Osteoporos Int，2016，27（1）：367-376.