益生菌治疗寻常性银屑病的随机、双盲、对照研究

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Abstract Objective To investigate the randomized,double blind,and control study of Probiotics in the treatment of psoriasis vulgaris and to analyze the curative effect and application value of Probiotics in the clinical treatment of psoriasis vulgaris.Methods 50 patients with psoriasis vulgaris were treated in our hospital from June to October 2016 were evenly divided into two groups by random,double-blind,and comparison.The controlgroup(n=25)was used the Actretin Capsules for treatment,while on the basis of treatment in control group,the observation group(n=25)was accompanied it with Probiotics for treatment.The post-treatment clinical efficiency,skin lesion area before and after treatment,severity index scores(PASI)before and after the treatment were comprared after 3 months.Results The total effective rate in the observation group was 92%(23/25),which was significantly higher than that in the control group of 72%(18/25),with significant difference (P＜0.05).Before treatment,there was no significant difference in PASI score between two groups (P＞0.05),while after treatment,the PASI score of the observation group was (6.82±4.22)points,which was significantly lower than that of the control group (10.76±5.35)points,with significant difference (P＜0.05).Conclusion In the therapeutic process of psoriasis vulgaris,both the conventional treatment and Probiotics treatment can significantly improve the efficacy,and reduce the PASI score,it is worthy of promotion.

Key words： Probiotics Psoriasis vulgaris PASI

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	LU Xiu-yi

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LU Xiu-yi. The randomized,double blind and control study of Probiotics in the treatment of psoriasis vulgaris[J]. 中国当代医药, 2017, 24(8): 47-49.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2017/V24/I8/47

[1]	宋晓静.消银颗粒治疗寻常型银屑病43例[J].中国药业，2013，22（4）：82.
[2]	万焰，蒋亚辉，邓玲俐，等.夫西地酸乳膏联合卤米松乳膏治疗寻常型银屑病的疗效及安全性[J].昆明医科大学学报，2016，37（2）：115-118.
[3]	张春红，张春敏，杜锡贤，等.中药熏蒸联合紫外线照射治疗寻常型银屑病的疗效观察[J].中华物理医学与康复杂志，2011，33（12）：937-939.
[4]	彭丹，席建元，祁林，等.银屑平丸联合阿维A胶囊治疗寻常型银屑病的疗效观察[J].中国中西医结合皮肤性病学杂志，2015，14（1）：41-42.
[5]	邹敏.阿维A和复方甘草酸苷治疗寻常型银屑病70例的疗效观察[J].贵阳中医学院学报，2013，35（4）：198-200.
[6]	孙小华，付英.益生菌与人体健康研究[J].中国卫生产业，2015，12（21）：162-164.
[7]	Takeda K，Suzuki T，Shimada SI，et al.Interleukin-12 is in鄄volved in the enhancement of human natural killer cell ac鄄tivity by Lactobacillus casei Shirota[J].Clini Exp Immunol，2006，146（1）：109-115.
[8]	Lee YK，Turner H，Maynard CL，et al.Late developmental plasticity in the T helper17 lineage[J].Immunity，2009，30（1）：92-107．
[9]	刘盼盼，匡叶红，张江林，等.阿维A与氨甲蝶呤治疗重度斑块型银屑病的疗效[J].中南大学学报（医学版），2016，41（8）：804-808.
[10]	李娜.益生菌对炎症性肠病的治疗作用分析[J].北方药学，2014，19（5）：24-25.
[11]	刘齐，孙美玲，王鲁峰，等.益生菌的功能活性及其分子机理探究的研究进展[J].中国酿造，2014，33（1）：14-19.
[12]	姜丽亚，郭震，戴景斌，等.益生菌治疗成人特应性皮炎疗效评价[J].中国麻风皮肤病杂志，2014，28（4）：205-207.
[13]	苏惠春，姚煦，王宝玺，等.皮肤微生物群与特应性皮炎[J].中华皮肤科杂志，2016，49（10）：754-757.
[14]	黄晓兵.中西医结合治疗150例寻常性银屑病疗效分析[J].实用皮肤病学杂志，2015，27（5）：371-372，375.
[15]	陈向齐，欧阳文杰，吴洁，等.白芍总苷联合阿维A和窄谱中波紫外线治疗寻常性银屑病临床观察[J].实用皮肤病学杂志，2014，28（1）：19-21，24.