|
|
Application of image-guided radiotherapy based on kV in thoracic tumor |
QIU Min-min REN Yu-feng ZHONG Jia-jian LIN Ze-huang ZHAO Wen-bin DENG Yong-jin WANG Zhen-yu WEN Bi-xiu▲ |
Department of Radiotherapy,the First Hospital Affiliated to Sun Yet-sen University,Guangdong Province,Guangzhou 510080,China |
|
|
Abstract ObjectiveTo analyze the inter-and intra-fractional setup errors of thoracic tumors using kilovolt-image guided radiotherapy (kV-IGRT),and to study the influence of kV image guidance on the accuracy of intensity modulated radiotherapy(IMRT)of thoracic tumors.Methods10 patients with thoracic tumors in our hospital from March to October in 2016 were selected,and the Varian Novalis Tx Linear Accelerator with on board image (OBI)system was used for daily image scanning before radiotherapy,if the bed needs to be moved,image scanning after the moving bed and scanning after radiotherapy was carried out.After the automatic reconstruction of the scanned image,the CT image of the treatment plan was registered,and the setup error of the patient′s Vrt,Lng,Lat were obtained and analyzed statistically.Results688 sets of images were obtained,the pre-radiotherapy setup error of Vrt,Lng,Lat were (-0.03±2.06),(0.16± 2.69),(0.18±2.28)mm,respectively.The setup error after the moving bed were(0.65±0.92),(0.65±0.93),(0.61±0.80)mm,respectively.The post-radiotherapy setup error were (-0.08±1.12),(0.32±1.13),(0.16±1.08)mm,respectively.ConclusionDaily kV-IGRT can significantly reduce the setup error of radiotherapy for thoracic tumors,and is of great significance for improving the accuracy of IMRT for thoracic tumors.
|
|
|
|
|
[1] |
Sun Y,Lu Y,Cheng S,et al.Interfractional variations of tumor centroid position and tumor regression during stereotactic body radiotherapy for lung tumor[J].Biomed Res Int,2014,2014:372738.
|
[2] |
Wu Z,Xie C,Hu M,et al.Dosimetric benefits of IMRT and VMAT in the treatment of middle thoracic esophageal cancer:is the conformal radiotherapy still an alternative option?[J]. J Appl Clin Med Phys,2014,15(3):4641.
|
[3] |
王义海,柔倩,张瑾熔,等.15例非小细胞肺癌IMRT计划与IGRT计划剂量学比较研究[J].新疆医科大学学报,2014,37(1):97-100.
|
[4] |
尚凯,迟子峰,王军,等.胸段食管癌IGRT中摆位误差分析[J].中华放射肿瘤学杂志,2015,24(1):70-73.
|
[5] |
Kong FM,Zhao J,Wang J,et al.Radiation dose effect in locally advanced non-small cell lung cancer[J].J Thorac Dis,2014,6(4):336-347.
|
[6] |
戴建荣,胡逸民.图像引导放疗的实现方式[J]中华放射肿瘤学杂志,2006,15(2):132-135.
|
[7] |
岳丹,杨永净,赵玲,等.kV-CBCT图像引导鼻咽癌调强放疗的精确性研究[J].中华放射医学与防护杂志,2016,36(3):211-215.
|
[8] |
Sonke JJ,Belderbos J.Adaptive radiotherapy for lung cancer[J]. Semin Radiat Oncol,,2010,20(2):94-106.
|
[9] |
车少敏,惠蓓娜,张晓智,等.IGRT在颈段、胸上段食管癌放疗中的应用[J].现代肿瘤医学,2013,21(1):96-100.
|
[10] |
Elsayad K,Kriz J,Reinartz G,et al.Cone-beam CT-guided radiotherapy in the management of lung cancer:Diagnostic and therapeutic value[J].Strahlenther Onkol,2016,192(2):83-91.
|
[11] |
吴钦宏,李高峰,王婵,等.基于锥形束CT体部肿瘤图像引导放疗的摆位误差分析[J].中华放射肿瘤学杂志,2012,21(1):68-71.
|
[12] |
曹晓辉,刘明,翟福山,等.CBCT图像引导下胸部肿瘤放疗摆位误差及其外放边界[J].中华放射肿瘤学杂志,2014,23(1):53-55.
|
[13] |
Alaei P,Spezi E.Imaging dose from cone beam computed tomography in radiation therapy[J].Phys Med,2015,31(7):647-658.
|
[14] |
Kan MW,Leung LH,Wong W,et al.Radiation dose from cone beam computed tomography for image-guided radiation therapy[J].Int J Radiat Oncol Biol Phys,2008,70(1):272-279.
|
[15] |
李娜,张旭,尹策,等.兆伏级锥形束CT所致剂量与体重指数的关系[J].中华放射肿瘤学杂志,2013,22(4):324-325.
|
[16] |
Ciardo D,Alterio D,Jereczek-Fossa BA,et al.Set-up errors in head and neck cancer patients treated with intensity modulated radiation therapy:quantitative comparison between three-dimensional cone-beam CT and two-dimensional kilovoltage images[J].Phys Med,2015,31(8):1015-1021.
|
[17] |
尹勇,朱健,李建彬,等.锥形束CT图像拼接技术的实现及其临床应用研究[J].中华放射肿瘤学杂志,2008,17(5):391-394.
|
[19] |
Van Herk M.Different styles of image-guided radiotherapy[J]. Semin Radiat Oncol,2007,17(4):258-267.
|
[18] |
Yan H,Wang X,Shi F,et al.Towards the clinical implementation of iterative low-dose cone-beam CT reconstruction in image-guided radiation therapy:cone/ring artifact correction and multiple GPU implementation[J].Med Phys,2014,41(11):111912.
|
[20] |
Sejpal SV,Amos RA,Bluett JB,et al.Dosimetric changes resulting from patient rotational setup errors in proton therapy prostate plans[J].Int J Radiat Oncol Biol Phys,2009,75(1):40-48.
|
|
|
|