|
|
|
| Application effect of Oxycodone combined with Propofol anesthesia in colonoscopy |
| LUO Xing-liao1 XIAO Jian1 LI Quan2 JIN Qi-chen3 NIE Li-jie1 HU Yi1▲ |
1.Department of Anesthesiology,General Hospital of North China Petroleum Administration Bureau,Hebei Province,Renqiu 062552,China;
2.Department of Surgery,the Second Hospital of North China Petroleum Administration Bureau, Hebei Province,Renqiu 062552,China;
3.Department of Gynecology,Jingxia Hospital of North China Petroleum Administration Bureau,Hebei Province,Renqiu 062552,China |
|
|
|
|
Abstract ObjectiveTo explore the efficacy of Oxycodone combined with Propofol in colonoscopy,and to provides the reference for its clinical application.MethodsFrom March 2015 to October 2016,100 patients undergoing colonoscopy in our hospital were selected and randomly divided into the Oxycodone group and the Fentanyl group,50 cases in each group.The oxycodone group was given Oxycodone combined with Propofol,and the fentanyl group was given Fentanyl combined with Propofol.The anesthesia effect in the two groups was compared.ResultsThere were no differences in anesthesia induction time,wake up time,heart rate,breathing rate,systolic blood pressure,diastolic pressure in the two groups(P＞0.05).The narcotic success dose,wake up dose and the EC50in the Oxycodone group was lower than that in the Fentanyl group,with significant difference (P＜0.05).The incidence rate of respiratory depression in the Oxycodone group was lower than that in the Fentanyl group,with significant difference (P＜0.05).ConclusionUnder the same anesthesia and anesthesia recovery,Oxycodone combined with Propofol in colonoscopy is safe and effective,and with less Propofol dosage.
|
|
|
|
|
|
| [1] |
Triantafillidis JK，Merikas E，Nikolakis D，et al.Sedation in gastrointestinal endoscopy：current issues[J].World J Gastroenterol，2013，19（4）：463-481.
|
| [2] |
李文波，徐树生，赵玉国，等.舒芬太尼对直肠癌根治术患者Th1/Th2平衡的影响[J].中国现代医学杂志，2012，22（2）：51-54.
|
| [3] |
Chinnery GE，Krige JE，Bornman PC，et al.Endoscopic management of bile leaks after laparoscopic cholecystectomy[J]. S Afr J Surg，2013，51（4）：116-121.
|
| [4] |
崔慧艳，全松石，黄学洙.右美托咪定与丙泊酚在直肠癌磁共振检查中的效果对比[J].中国现代医学杂志，2015，25（22）：83-85.
|
| [5] |
Dahan A，Aarts L，Smith TW.Incidence，reversal，and prevention of opioid-induced respiratory depression[J].Anesthesiology，2010，112（1）：226-238.
|
| [6] |
郭冰，赵洪伟，李锦成.不同剂量瑞芬太尼复合异丙酚用于结肠镜诊疗术麻醉效果的比较[J].中华麻醉学杂志，2013，33（4）：459-461.
|
| [7] |
陈莹莹，张宗泽，刘汉兴，等.羟考酮或氢吗啡酮复合异丙酚麻醉用于结肠镜诊疗术的效果[J].中华麻醉学杂志，2015，35（6）：724-726.
|
| [8] |
钱志伟，李立志.羟考酮芬太尼复合丙泊酚用于无痛人流的疗效观察[J].医学理论与实践，2015，28（16）：2180-2181.
|
| [9] |
Eberl S，Polderman JA，Preckel B，et al.Is“really conscious”sedation with solely an opioid an alternative to every day used sedation regimes for colonoscopies in a teaching hospital Midazolam，fentanyl，propofol/alfentanil，or alfentanil only for colonoscopy：a randomized trial[J].Tech Coloproctol，2014，18（8）：745-752.
|
| [10] |
张贝.盐酸羟考酮（oxycodone hydrochloride）[J].中国药物化学杂志，2011，21（2）：166.
|
| [11] |
田珺.舒芬太尼符合异丙酚麻醉用于结肠镜诊治中的效果观察[J].中国实用医药，2012，7（29）：164-165.
|
| [12] |
谢文钦，李扬亿，谢文吉，等.年龄因素对异丙酚抑制胃镜检查术内脏性疼痛效力的影响[J].中华麻醉学杂志，2014，34（8）：956-958.
|
| [13] |
薛军.舒芬太尼复合异丙酚麻醉用于结肠镜诊治效果观察[J].临床合理用药杂志，2014，7（25）：56.
|
| [14] |
黎曙光，张龙，阮国永，等.咪唑安定联合异丙酚在电子胃肠镜检查术中的临床应用[J].中国当代医药，2011，18 （23）：85-86，88.
|
| [15] |
吕建瑞，田俊斌，薛荣亮，等.盐酸羟考酮注射液联合丙泊酚闭环靶控输注在老年患者无痛肠镜中的应用[J].西部医学，2015，27（10）：1481-1484.
|
|
|
|
